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Study · Not a test of the peptide alone · 2023

5 results

Optimized approach for active peptides identification in Cerebrolysin by nanoLC-MS.

Yang B, Li Y, Guo W, Zhang Q, Pan L, Duan K, Zhang P, Ren L, Zhang W, Wang Q, Kong D

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences17 May 2023Cited by 1 (Europe PMC)

PMID37220681 (opens in a new tab)DOI10.1016/j.jchromb.2023.123755 (opens in a new tab)PepBankPUB-37220681
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study5

No result from this study comes from a test of the peptide.

Studies that did not test the peptide alone5

In this study, Cerebrolysin was a lab tool or a carrier, part of a mix, or the subject of a lab method. These results are not evidence about taking Cerebrolysin.

  1. 01LabNot a test of Cerebrolysin aloneIn vitro (cell-free)Other

    In lab tests, MCX extraction with PEAKS yielded the highest number of detected Cerebrolysin peptides.

    In plain wordsIn lab tests, MCX extraction with PEAKS detected the most Cerebrolysin peptides.

    Peptide
    Cerebrolysin
    Outcome
    IncreasePeptide detection yield
    Study

    n: not reported in source

    Outcome group
    Product quality and purity · Pharmacology

    Source sentences

    Summary
    Results showed that the number of peptides obtained by the MCX method coupled with PEAKS was the highest and the method was the most stable.

    In this study, Cerebrolysin was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Cerebrolysin.

  2. 02LabNot a test of Cerebrolysin aloneIn vitro (cell-free)Other

    In lab tests, MCX extraction with PEAKS was the most stable Cerebrolysin peptide detection method.

    In plain wordsIn lab tests, MCX extraction with PEAKS was the most stable Cerebrolysin detection method.

    Peptide
    Cerebrolysin
    Outcome
    IncreaseMethod stability
    Study

    n: not reported in source

    Outcome group
    Product quality and purity · Pharmacology

    Source sentences

    Summary
    Results showed that the number of peptides obtained by the MCX method coupled with PEAKS was the highest and the method was the most stable.

    In this study, Cerebrolysin was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Cerebrolysin.

  3. 03LabNot a test of Cerebrolysin aloneIn vitro (cell-free)Other

    In lab tests, some Cerebrolysin peptides matched myelin basic protein and tubulin beta chain.

    In plain wordsIn lab tests, some Cerebrolysin peptides matched myelin basic protein and tubulin beta chain.

    Peptide
    Cerebrolysin
    Outcome
    Not applicablePeptide protein origins
    Study

    n: not reported in source

    Outcome group
    Product quality and purity · Pharmacology

    Source sentences

    Summary
    In addition, this study found that some peptides in CBL were present in myelin basic protein and tubulin beta chain.

    In this study, Cerebrolysin was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Cerebrolysin.

  4. 04Computer modelNot a test of Cerebrolysin aloneIn silicoOther

    Computer analysis identified LLNLQPPPR and LSPSLRLP as potentially anti-inflammatory neuroprotective peptides in Cerebrolysin.

    In plain wordsComputer analysis predicted that LLNLQPPPR and LSPSLRLP in Cerebrolysin might reduce inflammation and protect neurons.

    Peptide
    Cerebrolysin
    Outcome
    Not applicablePredicted anti-inflammatory peptides
    Study

    n: not reported in source

    Outcome group
    Product quality and purity · Pharmacology

    Source sentences

    Summary
    Bioinformatic analysis of the detected peptides showed that two anti-inflammatory peptides (LLNLQPPPR and LSPSLRLP) and an antioxidant peptide (WPFPR) might be neuroprotective peptides in CBL.

    In this study, Cerebrolysin was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Cerebrolysin.

  5. 05Computer modelNot a test of Cerebrolysin aloneIn silicoOther

    Computer analysis identified WPFPR as a potentially antioxidant neuroprotective peptide in Cerebrolysin.

    In plain wordsComputer analysis predicted that WPFPR in Cerebrolysin might have antioxidant activity and protect neurons.

    Peptide
    Cerebrolysin
    Outcome
    Not applicablePredicted antioxidant peptide
    Study

    n: not reported in source

    Outcome group
    Product quality and purity · Pharmacology

    Source sentences

    Summary
    Bioinformatic analysis of the detected peptides showed that two anti-inflammatory peptides (LLNLQPPPR and LSPSLRLP) and an antioxidant peptide (WPFPR) might be neuroprotective peptides in CBL.

    In this study, Cerebrolysin was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Cerebrolysin.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    14 Oct 2026, 05:02 UTC

    Study results updated

  2. Version 1

    14 Oct 2026, 01:46 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

Publication types

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