Skip to content

Study · Measured the body's own peptide · 2025

2 results

Oxytocin as a Biomarker of Differential Effects to SPACE vs. CBT Treatment of Child Anxiety Disorders.

Zilcha-Mano S, Orbach M, Malka M, Lebowitz ER

Journal of clinical child and adolescent psychology : the official journal for the Society of Clinical Child and Adolescent Psychology, American Psychological Association, Division 5311 May 2023Cited by 4 (Europe PMC)

PMID37166402 (opens in a new tab)PMCIDPMC10638466 (opens in a new tab)DOI10.1080/15374416.2023.2188557 (opens in a new tab)PepBankPUB-37166402
Read at sourcePubMedAsk about this study
Jump to 2 results

Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: CC BY-NC-ND. Results still quote short attributed sentences.

Results from this study2

No result from this study comes from a test of the peptide.

Natural levels measured2

These results measure the body's own peptide. Nobody was given the peptide. They are not evidence about taking it. They are left out of key results, evidence counts and charts.

  1. 01HumanEndogenous levelRandomized controlled trialOther

    In children with anxiety disorders treated with SPACE, higher baseline salivary oxytocin and a rise in oxytocin after a positive mother-child interaction predicted greater treatment efficacy.

    In plain wordsIn children with anxiety, higher natural oxytocin levels and a rise after a positive interaction predicted better results from SPACE treatment.

    Peptide
    Oxytocin
    Outcome
    Not applicableChild salivary oxytocin as predictor of response to SPACE
    Study

    n: not reported in source

    Outcome group
    Endogenous peptide levels · Mental health and mood

    Source sentences

    Summary
    The findings suggest that in SPACE, where the mother is the main agent of change, higher baseline levels of child OT, coupled with increases in OT following a positive mother-child interaction, predicted greater treatment efficacy.
    2 context sentences
    Summary · context
    A total of 124 mother-child dyads participated in the study.
    Summary · context
    Children's salivary OT levels were measured at baseline and again, immediately after an experimental dyadic interaction in the lab.

    This result measures the body's own Oxytocin. Nobody was given the peptide. It is not evidence about taking it.

  2. 02HumanEndogenous levelRandomized controlled trialOther

    In children with anxiety disorders treated with CBT, higher baseline salivary oxytocin and a fall in oxytocin after a mother-child interaction predicted greater treatment efficacy.

    In plain wordsIn children with anxiety, higher natural oxytocin levels and a fall after an interaction predicted better results from CBT.

    Peptide
    Oxytocin
    Outcome
    Not applicableChild salivary oxytocin as predictor of response to CBT
    Study

    n: not reported in source

    Outcome group
    Endogenous peptide levels · Mental health and mood

    Source sentences

    Summary
    By contrast, in CBT, where the child is the main agent of change, higher baseline levels of child OT, coupled with a decrease in OT following the interaction, predicted greater treatment efficacy.
    2 context sentences
    Summary · context
    A total of 124 mother-child dyads participated in the study.
    Summary · context
    Children's salivary OT levels were measured at baseline and again, immediately after an experimental dyadic interaction in the lab.

    This result measures the body's own Oxytocin. Nobody was given the peptide. It is not evidence about taking it.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    11 Oct 2026, 00:50 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 02:48 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

PepBank is a research reference. Talk to a doctor before you use any peptide.