Skip to content

Study · Measured the body's own peptide · 2023

3 results

Serum MOTS-C Levels are Decreased in Obese Children and Associated with Vascular Endothelial Function.

Luo YH, Xie L, Li JY, Xie Y, Li MQ, Zhou L

Diabetes, metabolic syndrome and obesity : targets and therapy12 Apr 2023Cited by 14 (Europe PMC)

PMID37077579 (opens in a new tab)PMCIDPMC10106799 (opens in a new tab)DOI10.2147/dmso.s403934 (opens in a new tab)PepBankPUB-37077579
Read at sourcePubMedAsk about this study
Jump to 3 results

Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: CC BY-NC. Results still quote short attributed sentences.

Results from this study3

No result from this study comes from a test of the peptide.

Natural levels measured3

These results measure the body's own peptide. Nobody was given the peptide. They are not evidence about taking it. They are left out of key results, evidence counts and charts.

  1. 01HumanEndogenous levelObservational studyOther

    In obese children, serum MOTS‑C levels were lower than in healthy children.

    In plain wordsObese children had lower levels of the body's own MOTS‑c in blood than healthy children.

    Peptide
    MOTS-c
    Outcome
    DecreaseSerum MOTS-C in obese vs healthy children
    Study

    n = 443

    Comparator
    Healthy children
    Outcome group
    Mitochondrial function · Metabolic and weight

    Source sentences

    Summary
    Levels of serum MOTS-C and RHI were lower in the obese children compared with the healthy children
    1 context sentence
    Summary · context
    A total of 225 obese children (aged 8.1 ± 2.6 years) and 218 healthy children (aged 7.9 ± 2.2 years) were enrolled.

    This result measures the body's own MOTS-c. Nobody was given the peptide. It is not evidence about taking it.

  2. 02HumanEndogenous levelObservational studyOther

    In children, vascular endothelial function (RHI) was independently associated with serum MOTS‑C, with BMI and HDL cholesterol.

    In plain wordsIn children, blood vessel function was linked to the body's own MOTS‑c levels, along with BMI and HDL cholesterol.

    Peptide
    MOTS-c
    Outcome
    Direction not reportedAssociation of RHI with MOTS-C
    Study

    n: not reported in source

    Outcome group
    Mitochondrial function · Cardiovascular

    Source sentences

    Summary
    The RHI level was independently associated with body mass index, high-density lipoprotein cholesterol, and MOTS-C in linear regression analysis.
    1 context sentence
    Summary · context
    A total of 225 obese children (aged 8.1 ± 2.6 years) and 218 healthy children (aged 7.9 ± 2.2 years) were enrolled.

    This result measures the body's own MOTS-c. Nobody was given the peptide. It is not evidence about taking it.

  3. 03HumanEndogenous levelObservational studyOther

    Serum MOTS‑C significantly mediated the correlation between body mass index and RHI in children.

    In plain wordsIn children, the body's own MOTS‑c in blood helped explain the link between body mass index and blood vessel function.

    Peptide
    MOTS-c
    Outcome
    Not applicableMediation of BMI-RHI link by MOTS-C
    Study

    n: not reported in source

    Outcome group
    Mitochondrial function · Cardiovascular

    Measurements

    Mediating effect ratio
    9.12%
    BMI to RHI

    Source sentences

    Summary
    Further analysis showed a significant mediating effect of MOTS-C on the correlation between body mass index and RHI in children, with the ratio of mediating effect value of 9.12%.
    1 context sentence
    Summary · context
    A total of 225 obese children (aged 8.1 ± 2.6 years) and 218 healthy children (aged 7.9 ± 2.2 years) were enrolled.

    This result measures the body's own MOTS-c. Nobody was given the peptide. It is not evidence about taking it.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    10 Oct 2026, 08:19 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 02:47 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

PepBank is a research reference. Talk to a doctor before you use any peptide.