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Study · Randomized controlled trial · n = 30 · 2022

2 results

The efficacy of teriparatide (Cinnopar®) on bone repair in mandibular fractures: A single blinded randomized clinical trial.

Ebrahimi S, Navabazam A, Salemi F, Khaleghi F, Barzegar M, Saghafi F, Fallahzadeh H

Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery1 Dec 2022Cited by 1 (Europe PMC)

PMID36646571 (opens in a new tab)DOI10.1016/j.jcms.2022.12.002 (opens in a new tab)PepBankPUB-36646571
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

2 results from studies that gave the peptide. 2 results from people.

  1. 01HumanRandomized controlled trialEfficacy outcome

    In patients with mandibular fractures, teriparatide did not significantly affect bone repair compared with control.

    In plain wordsIn patients with jaw fractures, teriparatide did not significantly change bone repair compared with control.

    Peptide
    Teriparatide (PTH 1-34)
    Outcome
    No significant changeMandibular bone repair
    Study

    n = 30

    Comparator
    control group
    Outcome group
    Bone and joint · Musculoskeletal
    Studied dose
    Dose not stated · subcutaneous · 1 monthAs given in this study (human).

    Source sentences

    Summary
    There was no significant difference in bone repair between the two groups in this study (P > 0.05).
    2 context sentences
    Summary · context
    In this single-blind randomized controlled trial, 30 patients with a mandibular fracture hospitalized for open reduction internal fixation were randomly assigned to the intervention (I) (n = 15) and control (C) (n = 15) groups.
    Summary · context
    For 1 month, Group I received daily subcutaneous teriparatide injections.
  2. 02HumanRandomized controlled trialSafety outcome

    In patients with mandibular fractures, teriparatide had no significant effect on the postoperative complication rate compared with control.

    In plain wordsIn patients with jaw fractures, teriparatide did not significantly change the rate of complications after surgery compared with control.

    Peptide
    Teriparatide (PTH 1-34)
    Outcome
    No significant changePostoperative complication rate
    Study

    n = 30

    Comparator
    control group
    Outcome group
    Adverse events · Musculoskeletal
    Studied dose
    Dose not stated · subcutaneous · 1 monthAs given in this study (human).

    Source sentences

    Summary
    Teriparatide also had no effect on the postoperative complication rate in the control group (P > 0.05).
    Summary
    teriparatide did not affect bone fusion or postoperative complications
    2 context sentences
    Summary · context
    In this single-blind randomized controlled trial, 30 patients with a mandibular fracture hospitalized for open reduction internal fixation were randomly assigned to the intervention (I) (n = 15) and control (C) (n = 15) groups.
    Summary · context
    For 1 month, Group I received daily subcutaneous teriparatide injections.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Registered trials1

Trials this study reports on, or that list this study as a reference. Registry data from ClinicalTrials.gov.

1 trial · source ClinicalTrials.gov (opens in a new tab)

Status unknownPhase 4NCT06061354

Teriparatide on Maxillary Sinus Floor Osseointegration

Universidad de Valparaison = 4223 Aug 2023 to est. Dec 2024

Bone Regeneration

Trial pageClinicalTrials.govUpdated 30 Nov 2023

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    22 Oct 2026, 02:26 UTC

    Study results updated

  2. Version 1

    21 Oct 2026, 18:59 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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