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Study · Measured the body's own peptide · 2023

1 result

Periosteal topology creates an osteo-friendly microenvironment for progenitor cells.

Pan J, Li H, Jin K, Jiang H, Li K, Tang Y, Liu Z, Zhang K, Chen K, Xu Z, Wang H, Yang H, Niu J, Shi Q, Chen H

Materials today. Bio17 Dec 2022Cited by 9 (Europe PMC)

PMID36590983 (opens in a new tab)PMCIDPMC9800298 (opens in a new tab)DOI10.1016/j.mtbio.2022.100519 (opens in a new tab)PepBankPUB-36590983
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: CC BY-NC-ND. Results still quote short attributed sentences.

Results from this study1

No result from this study comes from a test of the peptide.

Natural levels measured1

These results measure the body's own peptide. Nobody was given the peptide. They are not evidence about taking it. They are left out of key results, evidence counts and charts.

  1. 01LabEndogenous levelIn vitro (cells)Mechanism

    In bone marrow stromal cells on aligned collagen, the aligned topology induced mechano-growth factor expression through Igf1 alternative splicing.

    In plain wordsIn lab tests, cells on aligned collagen made more of their own mechano-growth factor.

    Peptide
    MGF / PEG-MGF
    Outcome
    IncreaseMGF expression on aligned collagen
    Study

    n: not reported in source

    Bone marrow stromal cells on aligned collagen-coated fibers
    Outcome group
    Bone and joint · Musculoskeletal

    Source sentences

    Summary
    At last, we found the aligned topology of collagen induced mechano-growth factor expression as the result of Igf1 alternative splicing, guiding the progenitor cells behavior and osteogenic process in the periosteum.
    1 context sentence
    Summary · context
    We planted the bone marrow stromal cells(BMSCs), the regular shaped progenitor cells, on collagen-coated aligned fibers, presenting similar cell morphology as observed in the natural periosteum.

    This result measures the body's own MGF / PEG-MGF. Nobody was given the peptide. It is not evidence about taking it.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    13 Oct 2026, 21:44 UTC

    Study results updated

  2. Version 1

    13 Oct 2026, 16:31 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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