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Study · In vitro (cells) · 2022

1 result

Rational design of the zonulin inhibitor AT1001 derivatives as potential anti SARS-CoV-2.

Di Micco S, Rahimova R, Sala M, Scala MC, Vivenzio G, Musella S, Andrei G, Remans K, Mammri L, Snoeck R, Bifulco G, Di Matteo F and 4 more

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Vestuto V, Campiglia P, Márquez JA, Fasano A

European journal of medicinal chemistry19 Oct 2022Cited by 16 (Europe PMC)

PMID36332548 (opens in a new tab)PMCIDPMC9579148 (opens in a new tab)DOI10.1016/j.ejmech.2022.114857 (opens in a new tab)PepBankPUB-36332548
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study1

1 result from studies that gave the peptide. No result from this study comes from people.

  1. 01LabIn vitro (cells)Activity measurement

    In vitro antiviral tests showed lower biological activity for AT1001 than compound 4.

    In plain wordsIn lab tests, AT1001 showed lower antiviral activity than compound 4.

    Peptide
    Larazotide
    Outcome
    DecreaseAntiviral biological activity
    Study

    n: not reported in source

    Comparator
    Compound 4
    Outcome group
    Antiviral activity · Infection
    Studied dose
    Dose not stated

    Source sentences

    Summary
    In vitro antiviral tests indicate the improvement of biological activity of 4 respect to AT1001.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    22 Oct 2026, 02:26 UTC

    Study results updated

  2. Version 1

    21 Oct 2026, 18:59 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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