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Study · Not a test of the peptide alone · 2022

2 results

Identification and determination of structurally related peptide impurities in thymalfasin by liquid chromatography-high-resolution mass spectrometry.

Cheng Y, Wu P, Kan Y, Li M, Li H

Analytical and bioanalytical chemistry8 Oct 2022Cited by 2 (Europe PMC)

PMID36207535 (opens in a new tab)DOI10.1007/s00216-022-04336-5 (opens in a new tab)PepBankPUB-36207535
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

No result from this study comes from a test of the peptide.

Studies that did not test the peptide alone2

In this study, Thymosin alpha-1 was a lab tool or a carrier, part of a mix, or the subject of a lab method. These results are not evidence about taking Thymosin alpha-1.

  1. 01LabNot a test of Thymosin alpha-1 aloneIn vitro (cell-free)Other

    LC-hrMS separated, identified and quantified a total of twenty-three thymalfasin-related impurities in the ChP standard.

    In plain wordsIn lab tests, mass spectrometry found twenty-three impurities related to thymalfasin in the reference standard.

    Peptide
    Thymosin alpha-1
    Outcome
    Not applicableNumber of thymalfasin-related impurities in the ChP standard
    Study

    n: not reported in source

    Thymalfasin ChP standard and commercial materials analysed by LC-hrMS
    Outcome group
    Product quality and purity · Pharmacology

    Source sentences

    Summary
    A total of twenty-three thymalfasin-related impurities (> 0.1 mg/g) were separated, identified, and quantified in the ChP standard analyzed.

    In this study, Thymosin alpha-1 was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Thymosin alpha-1.

  2. 02LabNot a test of Thymosin alpha-1 aloneIn vitro (cell-free)Other

    Over half of the thymalfasin-related impurities arose directly or indirectly from the labile C-terminal asparagine residue.

    In plain wordsIn lab tests, more than half of the thymalfasin impurities came from one unstable end part of the peptide.

    Peptide
    Thymosin alpha-1
    Outcome
    Not applicableOrigin of impurities from the C-terminal asparagine
    Study

    n: not reported in source

    Thymalfasin ChP standard and commercial materials analysed by LC-hrMS
    Outcome group
    Product quality and purity · Pharmacology

    Source sentences

    Summary
    In particular, over half of the thymalfasin-related impurities were found directly or indirectly arising from the labile C-terminal asparagine (Asn) residue.

    In this study, Thymosin alpha-1 was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Thymosin alpha-1.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 3Current

    10 Oct 2026, 08:19 UTC

    Study results updated

  2. Version 2

    9 Oct 2026, 03:03 UTC

    Study data updated · source update from Europe PMC

  3. Version 1

    9 Oct 2026, 03:02 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

Publication types

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