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Study · Not a test of the peptide alone · 2022

1 result

Vasopressin neurons in the paraventricular hypothalamus promote wakefulness via lateral hypothalamic orexin neurons.

Islam MT, Rumpf F, Tsuno Y, Kodani S, Sakurai T, Matsui A, Maejima T, Mieda M

Current biology : CB30 Jul 2022Cited by 36 (Europe PMC)

PMID35907397 (opens in a new tab)DOI10.1016/j.cub.2022.07.020 (opens in a new tab)PepBankPUB-35907397
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study1

No result from this study comes from a test of the peptide.

Studies that did not test the peptide alone1

In this study, Melanotan II was a lab tool or a carrier, part of a mix, or the subject of a lab method. These results are not evidence about taking Melanotan II.

  1. 01AnimalNot a test of Melanotan II aloneAnimal study (in vivo)Mechanism

    Paraventricular vasopressin neurons mediated the arousal that the melanocortin receptor agonist melanotan II induced; melanotan II served as a stimulus to study these neurons.

    In plain wordsIn animals, vasopressin neurons in the hypothalamus mediated the arousal that melanotan II caused. The study used melanotan II as a tool.

    Peptide
    Melanotan II
    Outcome
    Not applicableArousal induced by melanotan-II depends on PVH AVP neurons
    Study

    n: not reported in source

    Outcome group
    Sleep · Sleep

    Source sentences

    Summary
    Moreover, PVHAVP neurons mediated the arousal induced by novelty stress and a melanocortin receptor agonist melanotan-II.

    In this study, Melanotan II was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Melanotan II.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    10 Oct 2026, 09:43 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 03:04 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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