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Study · Not a test of the peptide alone · 2022

1 result

GANT61 suppresses cell survival, invasion and epithelial-mesenchymal transition through inactivating AKT/mTOR and JAK/STAT3 pathways in anaplastic thyroid carcinoma.

Gao H, Wang W, Li Q

Cancer biology & therapy1 Dec 2022Cited by 19 (Europe PMC)

PMID35491899 (opens in a new tab)PMCIDPMC9067515 (opens in a new tab)DOI10.1080/15384047.2022.2051158 (opens in a new tab)PepBankPUB-35491899
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: CC BY-NC. Results still quote short attributed sentences.

Results from this study1

No result from this study comes from a test of the peptide.

Studies that did not test the peptide alone1

In this study, Colivelin was a lab tool or a carrier, part of a mix, or the subject of a lab method. These results are not evidence about taking Colivelin.

  1. 01LabNot a test of Colivelin aloneIn vitro (cells)Mechanism

    In anaplastic thyroid carcinoma cells, colivelin treatment promoted malignant behaviors.

    In plain wordsIn cells from anaplastic thyroid cancer, colivelin promoted malignant behaviors.

    Peptide
    Colivelin
    Outcome
    IncreaseMalignant behaviors
    Study

    n: not reported in source

    8505C and CAL-62 anaplastic thyroid carcinoma cells
    Outcome group
    Tumor growth · Cancer

    Source sentences

    Summary
    The following rescue experiments showed that SC79 or colivelin treatment promoted the malignant behaviors of ATC cells.
    2 context sentences
    Summary · context
    ATC cells (8505C and CAL-62) were treated with GANT61, followed by detection of cell proliferation, apoptosis, invasion and epithelial-mesenchymal transition (EMT) markers.
    Summary · context
    Following that, rescue experiments were conducted by SC79 (AKT activator) or colivelin (STAT3 activator) monotreatment or combined with GANT61 in ATC cells.

    In this study, Colivelin was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Colivelin.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    27 Oct 2026, 18:20 UTC

    Study results updated

  2. Version 1

    27 Oct 2026, 16:32 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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