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Study · Animal study (in vivo) · anas platyrhynchos domesticus · 2022

3 results

Sex differences in serum glucocorticoid levels and heterophil:lymphocyte ratios in adult pekin ducks (Anas platyrhynchos domesticus).

Tetel V, Tonissen S, Fraley GS

General and comparative endocrinology4 Jan 2022Cited by 17 (Europe PMC)

PMID34995644 (opens in a new tab)DOI10.1016/j.ygcen.2021.113975 (opens in a new tab)PepBankPUB-34995644
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study3

3 results from studies that gave the peptide. No result from this study comes from people.

  1. 01AnimalAnimal study (in vivo)Activity measurement

    In adult ducks, cosyntropin altered corticosterone secretion patterns dose-dependently versus controls (p = 0.0002), with sex differences (p = 0.0001).

    In plain wordsIn ducks, cosyntropin changed corticosterone secretion patterns compared with saline controls, with dose and sex differences.

    Peptide
    Cosyntropin
    Outcome
    MixedCorticosterone secretion pattern
    Study

    Anas platyrhynchos domesticusn: not reported in source

    Adult pekin ducks
    Comparator
    Saline controls
    Outcome group
    Stress hormones · Endocrine and hormones
    Studied dose
    0.0625 mg/kg, 0.031 mg/kg, or 0.016 mg/kg · intramuscularAs given in this study (Anas platyrhynchos domesticus).

    Source sentences

    Summary
    We observed that both GC were secreted in significantly (p = 0.0002) different patterns in a dose-dependent manner compared to controls, and that there was a significant (p = 0.0001) sex difference in both GC compared to saline controls.
    1 context sentence
    Summary · context
    To test this hypothesis, we injected artificial ACTH (cosyntropin; 0.0625 mg/kg, 0.031 mg/kg, or 0.016 mg/kg or saline as control) intramuscularly into adult drakes and hens (N = 10/sex/dose).
  2. 02AnimalAnimal study (in vivo)Activity measurement

    In adult ducks, cosyntropin altered cortisol secretion patterns dose-dependently versus controls (p = 0.0002), with sex differences (p = 0.0001).

    In plain wordsIn ducks, cosyntropin changed cortisol secretion patterns compared with saline controls, with dose and sex differences.

    Peptide
    Cosyntropin
    Outcome
    MixedCortisol secretion pattern
    Study

    Anas platyrhynchos domesticusn: not reported in source

    Adult pekin ducks
    Comparator
    Saline controls
    Outcome group
    Stress hormones · Endocrine and hormones
    Studied dose
    0.0625 mg/kg, 0.031 mg/kg, or 0.016 mg/kg · intramuscularAs given in this study (Anas platyrhynchos domesticus).

    Source sentences

    Summary
    We observed that both GC were secreted in significantly (p = 0.0002) different patterns in a dose-dependent manner compared to controls, and that there was a significant (p = 0.0001) sex difference in both GC compared to saline controls.
    1 context sentence
    Summary · context
    To test this hypothesis, we injected artificial ACTH (cosyntropin; 0.0625 mg/kg, 0.031 mg/kg, or 0.016 mg/kg or saline as control) intramuscularly into adult drakes and hens (N = 10/sex/dose).
  3. 03AnimalAnimal study (in vivo)Activity measurement

    In adult ducks, all cosyntropin doses produced sex differences in heterophil-to-lymphocyte responses versus controls (p = 0.004), without dose-dependent effects.

    In plain wordsIn ducks, cosyntropin produced sex differences in immune-cell ratio responses compared with controls, without dose-dependent effects.

    Peptide
    Cosyntropin
    Outcome
    MixedHeterophil to lymphocyte ratio response
    Study

    Anas platyrhynchos domesticusn: not reported in source

    Adult pekin ducks
    Comparator
    Saline controls
    Outcome group
    Immune response · Immune and inflammation
    Studied dose
    0.0625 mg/kg, 0.031 mg/kg, or 0.016 mg/kg · intramuscularAs given in this study (Anas platyrhynchos domesticus).

    Source sentences

    Summary
    Further, we observed that all doses of ACTH elicited a significant (p = 0.004) sex difference in the HLR response compared to controls, but no dose-dependent effects were noted.
    1 context sentence
    Summary · context
    To test this hypothesis, we injected artificial ACTH (cosyntropin; 0.0625 mg/kg, 0.031 mg/kg, or 0.016 mg/kg or saline as control) intramuscularly into adult drakes and hens (N = 10/sex/dose).

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    28 Oct 2026, 02:03 UTC

    Study results updated

  2. Version 1

    27 Oct 2026, 16:37 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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