Use of Cerebrolysin in combination with high-dose aspirin antithrombotic treatment of ischemic stroke: A case report.

Borisevich A, Veremeyuk K

Clinical case reports24 Sept 2021Cited by 1 (Europe PMC)

PMID34594556PMCIDPMC8462435DOI10.1002/ccr3.4863PepBankPUB-34594556

Summary

This clinical case is an example of a potential synergistic neuroprotective interaction of Cerebrolysin and high doses of aspirin. The case describes the significant recovery of neurological deficits in a patient with moderate ischemic stroke (NIHSS 12 points) caused by right posterior cerebral artery thrombosis (RPCAT) after treatment with Cerebrolysin in combination with high dose of aspirin. Within 7 days after the initiation of the treatment regimen, the NIHSS score improved to 3 points and a control MRI that was performed on the 10th day after stroke, showed a significant decrease of the ischemic area and cerebral edema zone. It further might have an evidence that the combination of Cerebrolysin with high-dose aspirin is safe and might have a synergistic effect in the treatment of ischemic stroke.

CC BYText from Europe PMC. Highlighted sentences are the source of results.

Results from this study3

No result from this study comes from a test of the peptide.

Studies that did not test the peptide alone3

In this study, Cerebrolysin was a lab tool or a carrier, part of a mix, or the subject of a lab method. These results are not evidence about taking Cerebrolysin.

01HumanNot a test of Cerebrolysin aloneCase report or seriesEfficacy outcome
In a patient with ischemic stroke, Cerebrolysin plus high-dose aspirin improved NIHSS to 3 points within 7 days.
In plain wordsIn a patient with ischemic stroke, Cerebrolysin plus high-dose aspirin improved NIHSS to 3 points within 7 days.
Peptide
Cerebrolysin
Outcome
DecreaseNIHSS score
Study
n = 1
Outcome group
Neuroprotection · Nervous system and cognition
Measurements
NIHSS score
12 points
before Cerebrolysin plus high-dose aspirin
NIHSS score
3 points
within 7 days after treatment initiation
Source sentences
Summary
Within 7 days after the initiation of the treatment regimen, the NIHSS score improved to 3 points
1 context sentence(design, population, supporting numbers)
Summary · context
The case describes the significant recovery of neurological deficits in a patient with moderate ischemic stroke (NIHSS 12 points) caused by right posterior cerebral artery thrombosis (RPCAT) after treatment with Cerebrolysin in combination with high dose of aspirin.
In this study, Cerebrolysin was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Cerebrolysin.
Show in the study text Report a problemFND-3459455601
02HumanNot a test of Cerebrolysin aloneCase report or seriesEfficacy outcome
In a patient with ischemic stroke, Cerebrolysin plus high-dose aspirin reduced the ischemic area on follow-up MRI.
In plain wordsIn a patient with ischemic stroke, Cerebrolysin plus high-dose aspirin reduced the ischemic area on follow-up MRI.
Peptide
Cerebrolysin
Outcome
DecreaseIschemic area
Study
n = 1
Outcome group
Neuroprotection · Nervous system and cognition
Source sentences
Summary
Within 7 days after the initiation of the treatment regimen, the NIHSS score improved to 3 points and a control MRI that was performed on the 10th day after stroke, showed a significant decrease of the ischemic area and cerebral edema zone.
1 context sentence(design, population, supporting numbers)
Summary · context
The case describes the significant recovery of neurological deficits in a patient with moderate ischemic stroke (NIHSS 12 points) caused by right posterior cerebral artery thrombosis (RPCAT) after treatment with Cerebrolysin in combination with high dose of aspirin.
In this study, Cerebrolysin was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Cerebrolysin.
Show in the study text Report a problemFND-3459455602
03HumanNot a test of Cerebrolysin aloneCase report or seriesEfficacy outcome
In a patient with ischemic stroke, Cerebrolysin plus high-dose aspirin reduced the cerebral edema zone on follow-up MRI.
In plain wordsIn a patient with ischemic stroke, Cerebrolysin plus high-dose aspirin reduced the cerebral edema zone on follow-up MRI.
Peptide
Cerebrolysin
Outcome
DecreaseCerebral edema zone
Study
n = 1
Outcome group
Neuroprotection · Nervous system and cognition
Source sentences
Summary
Within 7 days after the initiation of the treatment regimen, the NIHSS score improved to 3 points and a control MRI that was performed on the 10th day after stroke, showed a significant decrease of the ischemic area and cerebral edema zone.
1 context sentence(design, population, supporting numbers)
Summary · context
The case describes the significant recovery of neurological deficits in a patient with moderate ischemic stroke (NIHSS 12 points) caused by right posterior cerebral artery thrombosis (RPCAT) after treatment with Cerebrolysin in combination with high dose of aspirin.
In this study, Cerebrolysin was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Cerebrolysin.
Show in the study text Report a problemFND-3459455603

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

Version 2Current
14 Oct 2026, 05:02 UTC
Study results updated
Version 1
14 Oct 2026, 01:46 UTC
First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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Keywords

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