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Study · Not a test of the peptide alone · 2021

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DNA Dendrons as Agents for Intracellular Delivery.

Distler ME, Teplensky MH, Bujold KE, Kusmierz CD, Evangelopoulos M, Mirkin CA

Journal of the American Chemical Society19 Aug 2021Cited by 43 (Europe PMC)

PMID34410116 (opens in a new tab)PMCIDPMC8582297 (opens in a new tab)DOI10.1021/jacs.1c07240 (opens in a new tab)PepBankPUB-34410116
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study1

No result from this study comes from a test of the peptide.

Studies that did not test the peptide alone1

In this study, Thymosin alpha-1 was a lab tool or a carrier, part of a mix, or the subject of a lab method. These results are not evidence about taking Thymosin alpha-1.

  1. 01LabNot a test of Thymosin alpha-1 aloneIn vitro (cells)Activity measurement

    In cells, DNA dendrons conjugated to thymosin alpha‑1 at a single attachment site enhanced the cellular delivery and activity of the peptide.

    In plain wordsIn cells, linking thymosin alpha‑1 to a DNA dendron improved how well the peptide entered the cells and how well it worked.

    Peptide
    Thymosin alpha-1
    Outcome
    IncreaseCellular delivery and activity of DNA dendron-conjugated Tα1
    Study

    n: not reported in source

    dendritic cells
    Outcome group
    Immune response · Immune and inflammation

    Source sentences

    Summary
    when conjugated to peptides at a single attachment site, dendrons enhance the cellular delivery and activity of both the model ovalbumin 1 peptide and the therapeutically relevant thymosin alpha 1 peptide.

    In this study, Thymosin alpha-1 was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Thymosin alpha-1.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 3Current

    10 Oct 2026, 08:55 UTC

    Study results updated

  2. Version 2

    9 Oct 2026, 03:03 UTC

    Study data updated · source update from Europe PMC

  3. Version 1

    9 Oct 2026, 03:02 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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