In weaned infants with anemia, formula with 76 mg/100 g bovine lactoferrin raised fecal LL‑37 levels more than formula with 0 or 38 mg/100 g after 3 months.
In plain wordsIn infants with anemia, the highest lactoferrin dose in formula raised the body's own LL‑37 in stool more than the lower doses.
- Peptide
- LL-37
- Outcome
- IncreaseFecal LL-37 level after 3 months of bovine lactoferrin formula
- Study
n: not reported in source
- Comparator
- Other two groups (0 mg/100 g and 38 mg/100 g bLF)
- Outcome group
- Immune response · Immune and inflammation
Source sentences
The HBD-2, LL-37, sIgA, and calprotectin levels were significantly higher whereas the butyrate level was significantly lower in the FG2 infants than in infants in the other two groups after 3 mo of intervention (P < 0.05).
2 context sentences(design, population, supporting numbers)
The eligible infants were randomly assigned to fortified group 0 (FG0), fortified group 1 (FG1), or fortified group 2 (FG2) and were given formula fortified with 0 mg/100 g, 38 mg/100 g, and 76 mg/100 g of bLF, respectively, for 3 mo.
The morbidity of diarrhea and respiratory tract infections (RTIs), the duration of respiratory and diarrhea-related illnesses, and the levels of fecal human beta-defensin 2 (HBD-2), cathelicidin LL-37 (LL-37), secretory IgA (sIgA), butyrate, and calprotectin were assessed.
This result measures the body's own LL-37. Nobody was given the peptide. It is not evidence about taking it.