Skip to content

Study · Animal study (in vivo) · mouse · 2021

3 results

Enhanced Spontaneous Motor Recovery After Stroke in Mice Treated With Cerebrolysin.

DeBoer SR, Hubbard R, Mersha M, Pinilla Monsalve G, Winter S, Zeiler SR

Neurorehabilitation and neural repair6 May 2021Cited by 12 (Europe PMC)

PMID33955296 (opens in a new tab)DOI10.1177/15459683211000734 (opens in a new tab)PepBankPUB-33955296
Publisher pagePubMedAsk about this study
Jump to 3 results

Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study3

3 results from studies that gave the peptide. No result from this study comes from people.

  1. 01AnimalAnimal study (in vivo)Efficacy outcome

    In mice with stroke, daily Cerebrolysin starting on poststroke day 1 or day 8 produced complete prehension recovery despite delayed training.

    In plain wordsIn mice with stroke, Cerebrolysin produced complete prehension recovery despite delayed training compared with saline.

    Peptide
    Cerebrolysin
    Outcome
    IncreasePrehension recovery with delayed training
    Study

    mousen: not reported in source

    Photothrombotic stroke in caudal forelimb area
    Comparator
    Saline
    Outcome group
    Exercise and physical function · Nervous system and cognition
    Studied dose
    Dose not stated · intraperitonealAs given in this study (mouse).

    Source sentences

    Summary
    In contrast, we show complete recovery of prehension, despite a delay in rehabilitative training, when mice receive daily Cerebrolysin administration starting on poststroke day 1 or on poststroke day 8.
    2 context sentences
    Summary · context
    We then induced a photothrombotic stroke in the caudal forelimb area, after which we retrained animals on the prehension task in the presence or absence of Cerebrolysin after a 2-day or 8-day delay.
    Summary · context
    Mice received daily intraperitoneal Cerebrolysin or saline injections starting poststroke day 1 or poststroke day 7.
  2. 02AnimalAnimal study (in vivo)Efficacy outcome

    In mice with stroke, Cerebrolysin starting on poststroke day 1 produced recovery even without training.

    In plain wordsIn mice with stroke, Cerebrolysin produced recovery without training compared with saline.

    Peptide
    Cerebrolysin
    Outcome
    IncreasePrehension recovery without training
    Study

    mousen: not reported in source

    Photothrombotic stroke in caudal forelimb area
    Comparator
    Saline
    Outcome group
    Exercise and physical function · Nervous system and cognition
    Studied dose
    Dose not stated · intraperitonealAs given in this study (mouse).

    Source sentences

    Summary
    When Cerebrolysin is given on poststroke day 1, recovery occurred even in the absence of training.
    2 context sentences
    Summary · context
    We then induced a photothrombotic stroke in the caudal forelimb area, after which we retrained animals on the prehension task in the presence or absence of Cerebrolysin after a 2-day or 8-day delay.
    Summary · context
    Mice received daily intraperitoneal Cerebrolysin or saline injections starting poststroke day 1 or poststroke day 7.
  3. 03AnimalAnimal study (in vivo)Efficacy outcome

    In mice with stroke, stroke volumes were similar across groups, including Cerebrolysin and saline groups.

    In plain wordsIn mice with stroke, Cerebrolysin and saline groups had similar stroke volumes.

    Peptide
    Cerebrolysin
    Outcome
    No significant changeStroke volume
    Study

    mousen: not reported in source

    Photothrombotic stroke in caudal forelimb area
    Comparator
    Saline
    Outcome group
    Neuroprotection · Nervous system and cognition
    Studied dose
    Dose not stated · intraperitonealAs given in this study (mouse).

    Source sentences

    Summary
    Stroke volumes were similar across groups.
    2 context sentences
    Summary · context
    We then induced a photothrombotic stroke in the caudal forelimb area, after which we retrained animals on the prehension task in the presence or absence of Cerebrolysin after a 2-day or 8-day delay.
    Summary · context
    Mice received daily intraperitoneal Cerebrolysin or saline injections starting poststroke day 1 or poststroke day 7.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    14 Oct 2026, 05:02 UTC

    Study results updated

  2. Version 1

    14 Oct 2026, 01:46 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

PepBank is a research reference. Talk to a doctor before you use any peptide.