Skip to content

Study · Animal study (in vivo) · dairy cow · 2021

6 results

Pathogen dependent effects of high amounts of oxytocin on the bloodmilk barrier integrity during mastitis in dairy cows.

Strasser FJ, Feldmann M, Gross JJ, Müller ATM, Pfingstner H, Corti S, Stephan R, Bollwein H, Bruckmaier RM, Wellnitz O

Schweizer Archiv fur Tierheilkunde1 May 2021Cited by 1 (Europe PMC)

PMID33941509 (opens in a new tab)DOI10.17236/sat00302 (opens in a new tab)PepBankPUB-33941509
Publisher pagePubMedAsk about this study
Jump to 6 results

Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study6

6 results from studies that gave the peptide. No result from this study comes from people.

  1. 01AnimalAnimal study (in vivo)Efficacy outcome

    In dairy cows with mastitis, high-dose intravenous oxytocin did not change milk somatic cell count, whatever the involved pathogen.

    In plain wordsIn dairy cows with mastitis, high-dose oxytocin did not change the cell count in milk compared with no oxytocin.

    Peptide
    Oxytocin
    Outcome
    No significant changeMilk somatic cell count (SCC)
    Study

    dairy cown = 184

    Naturally occurring mastitis
    Comparator
    No oxytocin (control group)
    Outcome group
    Inflammation markers · Immune and inflammation
    Studied dose
    100 IU · intravenous · two injections (days 1 and 2)As given in this study (dairy cow).

    Source sentences

    Summary
    Oxytocin treatment did not affect any of the studied parameters independent of the involved pathogen.
    2 context sentences
    Summary · context
    Milk samples from 184 dairy cows from different farms were collected on day 1 (day of clinical examination and mastitis diagnosis) and on days 2, 3, 14, and 28.
    Summary · context
    Cows were randomly assigned to treatment (OT injections on days 1 and 2) or control group (no OT).
  2. 02AnimalAnimal study (in vivo)Efficacy outcome

    In dairy cows with mastitis, high-dose intravenous oxytocin did not change milk lactate dehydrogenase, whatever the involved pathogen.

    In plain wordsIn dairy cows with mastitis, high-dose oxytocin did not change milk lactate dehydrogenase compared with no oxytocin.

    Peptide
    Oxytocin
    Outcome
    No significant changeMilk lactate dehydrogenase (LDH)
    Study

    dairy cown = 184

    Naturally occurring mastitis
    Comparator
    No oxytocin (control group)
    Outcome group
    Inflammation markers · Immune and inflammation
    Studied dose
    100 IU · intravenous · two injections (days 1 and 2)As given in this study (dairy cow).

    Source sentences

    Summary
    Oxytocin treatment did not affect any of the studied parameters independent of the involved pathogen.
    2 context sentences
    Summary · context
    Milk samples from 184 dairy cows from different farms were collected on day 1 (day of clinical examination and mastitis diagnosis) and on days 2, 3, 14, and 28.
    Summary · context
    Cows were randomly assigned to treatment (OT injections on days 1 and 2) or control group (no OT).
  3. 03AnimalAnimal study (in vivo)Efficacy outcome

    In dairy cows with mastitis, high-dose intravenous oxytocin did not change milk serum albumin, whatever the involved pathogen.

    In plain wordsIn dairy cows with mastitis, high-dose oxytocin did not change milk serum albumin compared with no oxytocin.

    Peptide
    Oxytocin
    Outcome
    No significant changeMilk serum albumin (SA)
    Study

    dairy cown = 184

    Naturally occurring mastitis
    Comparator
    No oxytocin (control group)
    Outcome group
    Inflammation markers · Immune and inflammation
    Studied dose
    100 IU · intravenous · two injections (days 1 and 2)As given in this study (dairy cow).

    Source sentences

    Summary
    Oxytocin treatment did not affect any of the studied parameters independent of the involved pathogen.
    2 context sentences
    Summary · context
    Milk samples from 184 dairy cows from different farms were collected on day 1 (day of clinical examination and mastitis diagnosis) and on days 2, 3, 14, and 28.
    Summary · context
    Cows were randomly assigned to treatment (OT injections on days 1 and 2) or control group (no OT).
  4. 04AnimalAnimal study (in vivo)Efficacy outcome

    In dairy cows with mastitis, high-dose intravenous oxytocin did not change milk IgG, whatever the involved pathogen.

    In plain wordsIn dairy cows with mastitis, high-dose oxytocin did not change milk IgG compared with no oxytocin.

    Peptide
    Oxytocin
    Outcome
    No significant changeMilk IgG
    Study

    dairy cown = 184

    Naturally occurring mastitis
    Comparator
    No oxytocin (control group)
    Outcome group
    Immune response · Immune and inflammation
    Studied dose
    100 IU · intravenous · two injections (days 1 and 2)As given in this study (dairy cow).

    Source sentences

    Summary
    Oxytocin treatment did not affect any of the studied parameters independent of the involved pathogen.
    2 context sentences
    Summary · context
    Milk samples from 184 dairy cows from different farms were collected on day 1 (day of clinical examination and mastitis diagnosis) and on days 2, 3, 14, and 28.
    Summary · context
    Cows were randomly assigned to treatment (OT injections on days 1 and 2) or control group (no OT).
  5. 05AnimalAnimal study (in vivo)Efficacy outcome

    In dairy cows with mastitis, oxytocin was linked to a lower SCC only in quarters infected with Staphylococci other than Staphylococcus aureus.

    In plain wordsIn dairy cows with mastitis, oxytocin was linked to lower milk cell counts only in quarters infected with Staphylococci other than Staphylococcus aureus.

    Peptide
    Oxytocin
    Outcome
    DecreaseSCC in quarters infected with non-aureus staphylococci
    Study

    dairy cown: not reported in source

    Naturally occurring mastitis
    Comparator
    No oxytocin (control group)
    Outcome group
    Inflammation markers · Immune and inflammation
    Studied dose
    100 IU · intravenous · two injections (days 1 and 2)As given in this study (dairy cow).

    Source sentences

    Summary
    Only in quarters infected with Staphylococci other than Staphylococcus aureus a decreased SCC and increased IgG concentrations in quarters, where no pathogens were detected, were observed.
    2 context sentences
    Summary · context
    Milk samples from 184 dairy cows from different farms were collected on day 1 (day of clinical examination and mastitis diagnosis) and on days 2, 3, 14, and 28.
    Summary · context
    Cows were randomly assigned to treatment (OT injections on days 1 and 2) or control group (no OT).
  6. 06AnimalAnimal study (in vivo)Efficacy outcome

    In dairy cows with mastitis, oxytocin was linked to higher IgG concentrations in quarters where no pathogens were detected.

    In plain wordsIn dairy cows with mastitis, oxytocin was linked to higher milk IgG in quarters where no pathogens were detected.

    Peptide
    Oxytocin
    Outcome
    IncreaseMilk IgG in quarters without detected pathogens
    Study

    dairy cown: not reported in source

    Naturally occurring mastitis
    Comparator
    No oxytocin (control group)
    Outcome group
    Immune response · Immune and inflammation
    Studied dose
    100 IU · intravenous · two injections (days 1 and 2)As given in this study (dairy cow).

    Source sentences

    Summary
    Only in quarters infected with Staphylococci other than Staphylococcus aureus a decreased SCC and increased IgG concentrations in quarters, where no pathogens were detected, were observed.
    2 context sentences
    Summary · context
    Milk samples from 184 dairy cows from different farms were collected on day 1 (day of clinical examination and mastitis diagnosis) and on days 2, 3, 14, and 28.
    Summary · context
    Cows were randomly assigned to treatment (OT injections on days 1 and 2) or control group (no OT).

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    11 Oct 2026, 00:50 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 02:48 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

PepBank is a research reference. Talk to a doctor before you use any peptide.