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Study · Systematic review · 2021

3 results

A meta-analysis of hormone administration effects on cooperative behaviours: Oxytocin, vasopressin, and testosterone.

Yang X, Wang W, Wang XT, Wang YW

Neuroscience and biobehavioral reviews2 Apr 2021Cited by 25 (Europe PMC)

PMID33819546 (opens in a new tab)DOI10.1016/j.neubiorev.2021.03.033 (opens in a new tab)PepBankPUB-33819546
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study3

3 results from studies that gave the peptide. 3 results from people.

  1. 01HumanSystematic reviewEfficacy outcome

    In a meta-analysis of human studies, intranasal oxytocin had a moderate positive effect on cooperative behaviours.

    In plain wordsIn people, nasal oxytocin had a moderate positive effect on cooperative behavior in a meta-analysis.

    Peptide
    Oxytocin
    Outcome
    IncreaseCooperative behaviours after oxytocin
    Study

    n: not reported in source

    Outcome group
    Social behavior and cognition · Nervous system and cognition
    Studied dose
    Dose not stated · intranasalAs given in this study (human).

    Source sentences

    Summary
    Results revealed a moderate positive effect size of oxytocin intranasal administration
    1 context sentence
    Summary · context
    The current analysis included 41 studies involving 3,269 participants with a narrow age range.
  2. 02HumanSystematic reviewEfficacy outcome

    Participants with mental dysfunctions were less sensitive to oxytocin administration than other participants.

    In plain wordsPeople with mental dysfunctions responded less to oxytocin on cooperative behavior than other participants.

    Peptide
    Oxytocin
    Outcome
    DecreaseOxytocin effect in participants with mental dysfunctions
    Study

    n: not reported in source

    Outcome group
    Social behavior and cognition · Nervous system and cognition
    Studied dose
    Dose not stated · intranasalAs given in this study (human).

    Source sentences

    Summary
    Participants with mental dysfunctions were less sensitive to oxytocin and vasopressin administration.
    1 context sentence
    Summary · context
    The current analysis included 41 studies involving 3,269 participants with a narrow age range.
  3. 03HumanSystematic reviewEfficacy outcome

    Oxytocin administration was effective on cooperation in an in-group situation and for initial choices.

    In plain wordsOxytocin raised cooperation in in-group situations and for first choices in a meta-analysis.

    Peptide
    Oxytocin
    Outcome
    IncreaseOxytocin effect by situation and choice type
    Study

    n: not reported in source

    Outcome group
    Social behavior and cognition · Nervous system and cognition
    Studied dose
    Dose not stated · intranasalAs given in this study (human).

    Source sentences

    Summary
    Oxytocin administration was effective in an in-group situation and for initial choices, corroborating a Tit-for-Tat strategy.
    1 context sentence
    Summary · context
    The current analysis included 41 studies involving 3,269 participants with a narrow age range.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    9 Oct 2026, 18:17 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 02:48 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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