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Study · Randomized controlled trial · n = 101 · 2021

3 results

The effect of attachment security priming and oxytocin on physiological responses to trauma films and subsequent intrusions.

Karl A, Carnelley KB, Arikan G, Baldwin DS, Heinrichs M, Stopa L

Behaviour research and therapy13 Mar 2021Cited by 5 (Europe PMC)

PMID33780748 (opens in a new tab)DOI10.1016/j.brat.2021.103845 (opens in a new tab)PepBankPUB-33780748
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study3

2 results from studies that gave the peptide. 2 results from people.

  1. 01HumanRandomized controlled trialEfficacy outcome

    In volunteers, oxytocin administration did not reduce physiological arousal during attachment priming, compared with placebo.

    In plain wordsIn volunteers, oxytocin did not lower body arousal during priming compared with placebo.

    Peptide
    Oxytocin
    Outcome
    No significant changePhysiological arousal during priming
    Study

    n = 101

    Comparator
    Placebo
    Outcome group
    Stress hormones · Mental health and mood
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Secure attachment priming, but not oxytocin administration or the combination of both, was associated with reduced physiological arousal and increased parasympathetic activity during priming.
    1 context sentence
    Summary · context
    Using a double-blind, experimental mixed factorial design, 101 volunteers received either oxytocin or placebo and either secure attachment or neutral priming before watching a trauma film.
  2. 02HumanRandomized controlled trialEfficacy outcome

    In volunteers, oxytocin administration did not increase parasympathetic activity during attachment priming, compared with placebo.

    In plain wordsIn volunteers, oxytocin did not raise calming nervous system activity during priming compared with placebo.

    Peptide
    Oxytocin
    Outcome
    No significant changeParasympathetic activity during priming
    Study

    n = 101

    Comparator
    Placebo
    Outcome group
    Stress hormones · Mental health and mood
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Secure attachment priming, but not oxytocin administration or the combination of both, was associated with reduced physiological arousal and increased parasympathetic activity during priming.
    1 context sentence
    Summary · context
    Using a double-blind, experimental mixed factorial design, 101 volunteers received either oxytocin or placebo and either secure attachment or neutral priming before watching a trauma film.

Studies that did not test the peptide alone1

In this study, Oxytocin was a lab tool or a carrier, part of a mix, or the subject of a lab method. These results are not evidence about taking Oxytocin.

  1. 03HumanNot a test of Oxytocin aloneRandomized controlled trialEfficacy outcome

    In volunteers, the combination of oxytocin and secure attachment priming was not associated with reduced physiological arousal or increased parasympathetic activity.

    In plain wordsIn volunteers, oxytocin together with secure priming did not change body arousal or calming nervous system activity.

    Peptide
    Oxytocin
    Outcome
    No significant changePhysiological arousal and parasympathetic activity with oxytocin plus secure priming
    Study

    n = 101

    Outcome group
    Stress hormones · Mental health and mood

    Source sentences

    Summary
    Secure attachment priming, but not oxytocin administration or the combination of both, was associated with reduced physiological arousal and increased parasympathetic activity during priming.
    1 context sentence
    Summary · context
    Using a double-blind, experimental mixed factorial design, 101 volunteers received either oxytocin or placebo and either secure attachment or neutral priming before watching a trauma film.

    In this study, Oxytocin was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Oxytocin.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    11 Oct 2026, 00:50 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 02:48 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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