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Study · Randomized controlled trial · n = 63 · 2021

2 results

Oxytocin intensifies the mortality salience effect: Novel evidence for the social salience model of oxytocin.

Chen J, Luo YLL, Xie Y, Yang Z, Cai H

Hormones and behavior20 Jan 2021Cited by 3 (Europe PMC)

PMID33428924 (opens in a new tab)DOI10.1016/j.yhbeh.2020.104920 (opens in a new tab)PepBankPUB-33428924
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

2 results from studies that gave the peptide. 2 results from people.

  1. 01HumanRandomized controlled trialEfficacy outcome

    In healthy participants, intranasal oxytocin enhanced vigilance toward death-related images versus placebo.

    In plain wordsIn healthy people, nasal oxytocin increased attention to death-related images compared with placebo.

    Peptide
    Oxytocin
    Outcome
    IncreaseVigilance toward death-related images (dot-probe task)
    Study

    n = 63

    Comparator
    Placebo
    Outcome group
    Anxiety and mood · Mental health and mood
    Studied dose
    32 IU · intranasalAs given in this study (human).

    Source sentences

    Summary
    The results indicated that oxytocin enhanced participants' vigilance toward death-related images
    1 context sentence
    Summary · context
    In the current study, 63 participants intranasally received either 32 IU of oxytocin or a placebo and thereafter completed a visual dot-probe task consisting of death-related and non-death related images.
  2. 02HumanRandomized controlled trialEfficacy outcome

    In healthy participants, intranasal oxytocin increased anxiety about and fear of death versus placebo.

    In plain wordsIn healthy people, nasal oxytocin increased anxiety about and fear of death compared with placebo.

    Peptide
    Oxytocin
    Outcome
    IncreaseAnxiety about and fear of death
    Study

    n = 63

    Comparator
    Placebo
    Outcome group
    Anxiety and mood · Mental health and mood
    Studied dose
    32 IU · intranasalAs given in this study (human).

    Source sentences

    Summary
    The results indicated that oxytocin enhanced participants' vigilance toward death-related images as well as increased their anxiety about and fear of death.
    1 context sentence
    Summary · context
    In the current study, 63 participants intranasally received either 32 IU of oxytocin or a placebo and thereafter completed a visual dot-probe task consisting of death-related and non-death related images.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    11 Oct 2026, 00:50 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 02:48 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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