In healthy men, intranasal oxytocin did not significantly change motivational behaviour towards food in an approach-avoidance task versus placebo.
In plain wordsIn healthy men, oxytocin nasal spray did not change how strongly they were drawn to or away from food, compared with placebo.
- Peptide
- Oxytocin
- Outcome
- No significant changeMotivational approach-avoidance behaviour towards food
- Study
n = 33
- Comparator
- Placebo
- Outcome group
- Appetite and food intake · Metabolic and weight
- Studied dose
- Dose not stated · intranasalAs given in this study (human).
Source sentences
Most importantly, we did not observe any significant effects of oxytocin compared to placebo in motivational behaviour towards food.
2 context sentences(design, population, supporting numbers)
In the present study, we used a food-based approach-avoidance task (AAT) in a randomised, placebo-controlled, double-blind, cross-over design to compare intranasal oxytocin with a placebo.
Thirty-three healthy male participants (age = 25.12 ± 3.51 years; body mass index = 24.25 ± 2.48 kg/m2 ) completed the two-session study, one with placebo and the other with oxytocin.