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Study · Randomized controlled trial · n = 10 · 2021

2 results

Oxytocin Administration Increases Proactive Control in Men with Overweight or Obesity: A Randomized, Double-Blind, Placebo-Controlled Crossover Study.

Plessow F, Marengi DA, Perry SK, Lawson EA

Obesity (Silver Spring, Md.)22 Nov 2020Cited by 24 (Europe PMC)

PMID33225615 (opens in a new tab)PMCIDPMC8695366 (opens in a new tab)DOI10.1002/oby.23010 (opens in a new tab)PepBankPUB-33225615
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

2 results from studies that gave the peptide. 2 results from people.

  1. 01HumanRandomized controlled trialEfficacy outcome

    In men with overweight or obesity, intranasal oxytocin increased reaction times in the go task versus placebo.

    In plain wordsIn men with overweight or obesity, nasal oxytocin slowed reaction times in a choice task compared with placebo.

    Peptide
    Oxytocin
    Outcome
    IncreaseReaction time in the go task
    Study

    n = 10

    Comparator
    Placebo
    Outcome group
    Cognition and memory · Nervous system and cognition
    Studied dose
    24 IU · intranasal · single doseAs given in this study (human).

    Measurements

    Reaction time
    936 milliseconds
    oxytocin
    Reaction time
    833 milliseconds
    placebo

    Source sentences

    Summary
    After receiving oxytocin, compared with placebo, participants showed increased reaction times in the go task (mean [M] = 936 milliseconds vs. 833 millseconds; P = 0.012; 95% CI: 29 to 178)
    1 context sentence
    Summary · context
    In a randomized, double-blind, placebo-controlled crossover study of 24-IU single-dose intranasal oxytocin, 10 men with overweight or obesity completed a stop-signal task assessing ability and strategy to suppress behavioral impulses, in which they performed a choice-reaction task (go task) but had…
  2. 02HumanRandomized controlled trialEfficacy outcome

    In men with overweight or obesity, intranasal oxytocin reduced the percentage of stop errors versus placebo.

    In plain wordsIn men with overweight or obesity, nasal oxytocin led to fewer errors when stopping a response than placebo.

    Peptide
    Oxytocin
    Outcome
    DecreaseStop errors
    Study

    n = 10

    Comparator
    Placebo
    Outcome group
    Cognition and memory · Nervous system and cognition
    Studied dose
    24 IU · intranasal · single doseAs given in this study (human).

    Measurements

    Stop errors
    36.41%
    oxytocin
    Stop errors
    41.15%
    placebo

    Source sentences

    Summary
    and displayed fewer stop errors (M = 36.41% vs. 41.15%; P = 0.049; 95% CI: -9.43% to -0.03%).
    1 context sentence
    Summary · context
    In a randomized, double-blind, placebo-controlled crossover study of 24-IU single-dose intranasal oxytocin, 10 men with overweight or obesity completed a stop-signal task assessing ability and strategy to suppress behavioral impulses, in which they performed a choice-reaction task (go task) but had…

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    11 Oct 2026, 00:50 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 02:48 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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