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Study · Measured the body's own peptide · 2020

2 results

Effect of different muscle contraction mode on the expression of Myostatin, IGF-1, and PGC-1 alpha family members in human Vastus Lateralis muscle.

Taghibeikzadehbadr P, Shirian S, Sabouri M

Molecular biology reports22 Nov 2020Cited by 3 (Europe PMC)

PMID33222041 (opens in a new tab)DOI10.1007/s11033-020-06017-x (opens in a new tab)PepBankPUB-33222041
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

No result from this study comes from a test of the peptide.

Natural levels measured2

These results measure the body's own peptide. Nobody was given the peptide. They are not evidence about taking it. They are left out of key results, evidence counts and charts.

  1. 01HumanEndogenous levelNon-randomized trialMechanism

    In healthy men, IGF-1Ec mRNA in vastus lateralis muscle increased after an eccentric exercise bout.

    In plain wordsIn healthy men, one bout of eccentric exercise raised the body's own IGF-1Ec gene activity in thigh muscle.

    Peptide
    MGF / PEG-MGF
    Outcome
    IncreaseIGF-1Ec mRNA after eccentric contraction
    Study

    n = 5

    Comparator
    Pre-exercise baseline
    Outcome group
    Endogenous peptide levels · Musculoskeletal

    Source sentences

    Summary
    while the PGC1α-4 and IGF-1Ec significantly increased after eccentric contraction (p ≤ 0.05).
    2 context sentences
    Summary · context
    Here, we assessed the response of IGF-1Ea, IGF-1Eb, IGF-1Ec, PGC1α-1, PGC1α-4, and myostatin to the eccentric Vs. the concentric contraction in human skeletal muscle.
    Summary · context
    Ten healthy males were performed an acute eccentric and concentric exercise bout (n = 5 per group).

    This result measures the body's own MGF / PEG-MGF. Nobody was given the peptide. It is not evidence about taking it.

  2. 02HumanEndogenous levelNon-randomized trialMechanism

    In healthy men, changes in IGF-1Ec mRNA did not differ between eccentric and concentric exercise.

    In plain wordsIn healthy men, the rise in the body's own IGF-1Ec gene activity was not different after eccentric and concentric exercise.

    Peptide
    MGF / PEG-MGF
    Outcome
    No significant changeIGF-1Ec mRNA change, eccentric versus concentric contraction
    Study

    n = 5

    Comparator
    Concentric contraction
    Outcome group
    Endogenous peptide levels · Musculoskeletal

    Source sentences

    Summary
    It is intriguing to highlight that; no significant differences between groups were evident for changes in any variables following exercise bouts (p ≥ 0.05).
    2 context sentences
    Summary · context
    Here, we assessed the response of IGF-1Ea, IGF-1Eb, IGF-1Ec, PGC1α-1, PGC1α-4, and myostatin to the eccentric Vs. the concentric contraction in human skeletal muscle.
    Summary · context
    Ten healthy males were performed an acute eccentric and concentric exercise bout (n = 5 per group).

    This result measures the body's own MGF / PEG-MGF. Nobody was given the peptide. It is not evidence about taking it.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    13 Oct 2026, 21:44 UTC

    Study results updated

  2. Version 1

    13 Oct 2026, 16:31 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

Publication types

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