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Study · Measured the body's own peptide · 2021

3 results

Comparative study of the volume of the temporal lobe sections and neuropeptide effect in Alzheimer's patients and healthy persons.

Petekkaya E, Burakgazi G, Kuş B, Melek İM, Arpacı A

The International journal of neuroscience16 Oct 2020Cited by 11 (Europe PMC)

PMID33064056 (opens in a new tab)DOI10.1080/00207454.2020.1831490 (opens in a new tab)PepBankPUB-33064056
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study3

No result from this study comes from a test of the peptide.

Natural levels measured3

These results measure the body's own peptide. Nobody was given the peptide. They are not evidence about taking it. They are left out of key results, evidence counts and charts.

  1. 01HumanEndogenous levelObservational studyOther

    Patients with mild Alzheimer's disease had lower blood levels of the body's own oxytocin than healthy controls.

    In plain wordsPeople with mild Alzheimer's disease had lower levels of the body's own oxytocin than healthy people.

    Peptide
    Oxytocin
    Outcome
    DecreaseBlood oxytocin value in Alzheimer's disease
    Study

    n = 30

    Comparator
    Healthy control group
    Outcome group
    Cognition and memory · Nervous system and cognition

    Source sentences

    Summary
    The patient group had a statistically lower right hippocampus volume (p = 0.004) and OT values (p = 0.028)
    2 context sentences
    Summary · context
    The study comprised of a group of patients diagnosed with mild AD (n:15) and a Control group (n:15) (16 females, 14 males, mean age:72.90 ± 4.50).
    Summary · context
    Following a 10-minute hug test, blood samples were taken from all participants for oxytocin (OT) and arginine vasopressin (AVP) analyses.

    This result measures the body's own Oxytocin. Nobody was given the peptide. It is not evidence about taking it.

  2. 02HumanEndogenous levelObservational studyOther

    Oxytocin signal values rose with larger volume of the right parahippocampal gyrus, so the body's own oxytocin was positively correlated with this brain region's volume.

    In plain wordsHigher natural oxytocin signal values were linked to a larger volume of one brain region, the right parahippocampal gyrus.

    Peptide
    Oxytocin
    Outcome
    Not applicableCorrelation of oxytocin signal value with right parahippocampal gyrus volume
    Study

    n = 30

    Outcome group
    Cognition and memory · Nervous system and cognition

    Source sentences

    Summary
    OT signal values increased with a volume increase in the right parahippocampal gyrus (PHG_R)
    2 context sentences
    Summary · context
    The study comprised of a group of patients diagnosed with mild AD (n:15) and a Control group (n:15) (16 females, 14 males, mean age:72.90 ± 4.50).
    Summary · context
    Following a 10-minute hug test, blood samples were taken from all participants for oxytocin (OT) and arginine vasopressin (AVP) analyses.

    This result measures the body's own Oxytocin. Nobody was given the peptide. It is not evidence about taking it.

  3. 03HumanEndogenous levelObservational studyOther

    Blood oxytocin concentration, like arginine vasopressin concentration, rose with larger volume of the right parahippocampal gyrus.

    In plain wordsHigher natural oxytocin levels in blood were linked to a larger volume of one brain region, the right parahippocampal gyrus.

    Peptide
    Oxytocin
    Outcome
    Not applicableCorrelation of oxytocin concentration with right parahippocampal gyrus volume
    Study

    n = 30

    Outcome group
    Cognition and memory · Nervous system and cognition

    Source sentences

    Summary
    and OT conc. and AVP conc. values increased with increasing volume of the PHG_R.
    2 context sentences
    Summary · context
    The study comprised of a group of patients diagnosed with mild AD (n:15) and a Control group (n:15) (16 females, 14 males, mean age:72.90 ± 4.50).
    Summary · context
    Following a 10-minute hug test, blood samples were taken from all participants for oxytocin (OT) and arginine vasopressin (AVP) analyses.

    This result measures the body's own Oxytocin. Nobody was given the peptide. It is not evidence about taking it.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    11 Oct 2026, 00:50 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 02:49 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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