QR678 & QR678 Neo Hair Growth Formulations: A Cellular Toxicity & Animal Efficacy Study.

Kapoor R, Shome D, Vadera S, Kumar V, Ram MS

Plastic and reconstructive surgery. Global open25 Aug 2020Cited by 14 (Europe PMC)

PMID32983753PMCIDPMC7489598DOI10.1097/gox.0000000000002843PepBankPUB-32983753

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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: CC BY-NC-ND. Results still quote short attributed sentences.

Results from this study4

1 result from studies that gave the peptide. No result from this study comes from people.

01LabIn vitro (cells)Safety outcome
In human keratinocyte and fibroblast cell assays, all the factors, including copper tripeptide 1, were found to be safe.
In plain wordsIn human skin cells in the lab, none of the tested factors, including copper peptide, was found toxic.
Peptide
GHK-Cu
Outcome
No significant changeCytotoxicity in keratinocytes and fibroblasts
Study
humann: not reported in source
Human keratinocyte and fibroblast cells
Outcome group
Adverse events · Skin and wound
Studied dose
Dose not stated
Source sentences
Summary
On cytotoxicity study, all the factors were found to be safe in human keratinocyte cell and human fibroblast cell assay.
1 context sentence(design, population, supporting numbers)
Summary · context
The 3-2,5-diphenyl tetrazolium bromide assay was used to explore the cytotoxic effects of each factor used in the compositions in human keratinocyte cell and human fibroblast cell assays
Report a problemFND-3298375303

Studies that did not test the peptide alone3

In this study, GHK-Cu was a lab tool or a carrier, part of a mix, or the subject of a lab method. These results are not evidence about taking GHK-Cu.

02AnimalNot a test of GHK-Cu aloneAnimal study (in vivo)Efficacy outcome
In mice, injections of QR 678 and QR 678 Neo, which contain copper tripeptide 1 with growth factors, gave a positive response in the number of mice with hair growth at the injection sites.
In plain wordsIn mice, injections of a mixture of growth factors and copper peptide led to hair growth at the injection sites.
Peptide
GHK-Cu
Outcome
IncreaseHair growth at injection sites
Study
mousen: not reported in source
Mouse hair growth model
Outcome group
Skin and hair · Skin and wound
Source sentences
Summary
In both formulations, a positive response was observed with respect to the number of mice exhibiting hair growth at the injection sites.
1 context sentence(design, population, supporting numbers)
Summary · context
An in vivo analysis, wherein study animals were given intradermal QR 678 & QR 678 Neo injections, was conducted to assess whether the formulations produce hair growth.
In this study, GHK-Cu was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking GHK-Cu.
Report a problemFND-3298375301
03AnimalNot a test of GHK-Cu aloneAnimal study (in vivo)Efficacy outcome
In mice, the injections caused retention of hair in a 0.25-cm radius around the injection site.
In plain wordsIn mice, injections of a mixture of growth factors and copper peptide kept hair in a small area around the injection site.
Peptide
GHK-Cu
Outcome
IncreaseHair retention around injection site
Study
mousen: not reported in source
Mouse hair growth model
Outcome group
Skin and hair · Skin and wound
Source sentences
Summary
The injections caused retention of hair in a 0.25-cm radius around the injection site.
1 context sentence(design, population, supporting numbers)
Summary · context
An in vivo analysis, wherein study animals were given intradermal QR 678 & QR 678 Neo injections, was conducted to assess whether the formulations produce hair growth.
In this study, GHK-Cu was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking GHK-Cu.
Report a problemFND-3298375302
04AnimalNot a test of GHK-Cu aloneAnimal study (in vivo)Efficacy outcome
In animals given a chemotherapeutic agent, a positive response was reported; the abstract does not define the response.
In plain wordsIn animals given a chemotherapy drug, a positive response was reported, but the abstract does not say what it measured.
Peptide
GHK-Cu
Outcome
IncreaseResponse in secondary alopecia model
Study
n: not reported in source
Secondary alopecia animal model
Outcome group
Skin and hair · Skin and wound
Source sentences
Summary
A positive response was demonstrated in animals on treatment with the chemotherapeutic agent.
2 context sentences(design, population, supporting numbers)
Summary · context
Also, hair follicle viability was checked by intradermal injection of the pharmaceutical compositions in secondary alopecia.
Summary · context
An in vivo analysis, wherein study animals were given intradermal QR 678 & QR 678 Neo injections, was conducted to assess whether the formulations produce hair growth.
In this study, GHK-Cu was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking GHK-Cu.
Report a problemFND-3298375304

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

Version 3Current
9 Oct 2026, 18:17 UTC
Study results updated
Version 2
9 Oct 2026, 03:03 UTC
Study data updated · source update from Europe PMC
Version 1
9 Oct 2026, 02:56 UTC
First added · source update from Europe PMC

Subjects

Terms as the source lists them.

Publication types

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