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Study · Not a test of the peptide alone · 2020

3 results

Alternative Protocol Using Imipramine, Detomidine, and Oxytocin for Semen Collection in Stallion with Ejaculatory Dysfunction.

Cavalero TMS, Segabinazzi LGTM, Scheeren VFC, Canuto LEF, Gobato MLM, Papa FF

Journal of equine veterinary science6 Aug 2020Cited by 5 (Europe PMC)

PMID32972673 (opens in a new tab)DOI10.1016/j.jevs.2020.103205 (opens in a new tab)PepBankPUB-32972673
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study3

No result from this study comes from a test of the peptide.

Studies that did not test the peptide alone3

In this study, Oxytocin was a lab tool or a carrier, part of a mix, or the subject of a lab method. These results are not evidence about taking Oxytocin.

  1. 01AnimalNot a test of Oxytocin aloneAnimal study (in vivo)Efficacy outcome

    In a stallion with idiopathic ejaculatory dysfunction, a protocol of imipramine, detomidine and oxytocin produced ejaculation after other attempts had failed.

    In plain wordsIn one stallion that could not ejaculate, a protocol of three drugs including oxytocin produced ejaculation after earlier attempts failed.

    Peptide
    Oxytocin
    Outcome
    IncreaseEjaculation on ex copula semen collection
    Study

    horse (Quarter Horse stallion)n = 1

    Outcome group
    Sex hormones and fertility · Reproductive and sexual health

    Source sentences

    Summary
    However, a protocol consisted by the association of imipramine (3 mg/kg/v.o.), detomidine (0.02 mg/kg/i.v.), and oxytocin (20 U.I./i.v.) successfully produced ejaculation in this stallion.
    2 context sentences
    Summary · context
    A 7-year-old Quarter Horse stallion was admitted at the hospital with a history of ejaculatory failure for 12 months.
    Summary · context
    Based on clinical findings, the stallion was diagnosed with an idiopathic ejaculatory dysfunction; therefore, alternative attempts of semen collection were performed.

    In this study, Oxytocin was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Oxytocin.

  2. 02AnimalNot a test of Oxytocin aloneAnimal study (in vivo)Efficacy outcome

    In a stallion with ejaculatory dysfunction, semen collected with the imipramine, detomidine and oxytocin protocol had 87% total motility.

    In plain wordsIn one stallion, semen collected with a three-drug protocol including oxytocin had good sperm quality, with 87% of sperm moving.

    Peptide
    Oxytocin
    Outcome
    Not applicableSperm total motility of collected semen
    Study

    horse (Quarter Horse stallion)n = 1

    Outcome group
    Sex hormones and fertility · Reproductive and sexual health

    Measurements

    Total motility
    87%
    collected semen

    Source sentences

    Summary
    Semen with good sperm quality (87% of total motility) was obtained using the proposed protocol.
    2 context sentences
    Summary · context
    A 7-year-old Quarter Horse stallion was admitted at the hospital with a history of ejaculatory failure for 12 months.
    Summary · context
    Based on clinical findings, the stallion was diagnosed with an idiopathic ejaculatory dysfunction; therefore, alternative attempts of semen collection were performed.

    In this study, Oxytocin was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Oxytocin.

  3. 03AnimalNot a test of Oxytocin aloneAnimal study (in vivo)Efficacy outcome

    In a stallion with ejaculatory dysfunction, cryopreserved semen collected with the imipramine, detomidine and oxytocin protocol had satisfactory post-thaw sperm parameters.

    In plain wordsIn one stallion, frozen and thawed semen collected with a three-drug protocol including oxytocin had satisfactory sperm quality.

    Peptide
    Oxytocin
    Outcome
    Not applicablePost-thaw sperm parameters
    Study

    horse (Quarter Horse stallion)n = 1

    Outcome group
    Sex hormones and fertility · Reproductive and sexual health

    Source sentences

    Summary
    Semen was then processed for cryopreservation and post-thawed semen samples presented satisfactory sperm parameters.
    2 context sentences
    Summary · context
    A 7-year-old Quarter Horse stallion was admitted at the hospital with a history of ejaculatory failure for 12 months.
    Summary · context
    Based on clinical findings, the stallion was diagnosed with an idiopathic ejaculatory dysfunction; therefore, alternative attempts of semen collection were performed.

    In this study, Oxytocin was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Oxytocin.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    11 Oct 2026, 01:30 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 02:48 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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