Skip to content

Study · Animal study (in vivo) · mouse · 2020

2 results

CAPS2 deficiency induces proopiomelanocortin accumulation in pituitary and affects food intake behavior in mice.

Fujima S, Amemiya N, Arima T, Sano Y, Furuichi T

Neuroscience letters3 Sept 2020Cited by 3 (Europe PMC)

PMID32891671 (opens in a new tab)DOI10.1016/j.neulet.2020.135335 (opens in a new tab)PepBankPUB-32891671
Publisher pagePubMedAsk about this study
Jump to 2 results

Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

2 results from studies that gave the peptide. No result from this study comes from people.

  1. 01AnimalAnimal study (in vivo)Efficacy outcome

    In Caps2-knockout mice, low-dose melanotan-2 decreased food intake per body weight; no such effect was seen in wild-type mice.

    In plain wordsIn mice lacking CAPS2, a low dose of melanotan-2 reduced food intake per body weight.

    Peptide
    Melanotan II
    Outcome
    DecreaseFood intake per body weight after melanotan-2
    Study

    mousen: not reported in source

    Caps2-knockout mice
    Comparator
    Wild-type mice
    Outcome group
    Appetite and food intake · Metabolic and weight
    Studied dose
    low-doseAs given in this study (mouse).

    Source sentences

    Summary
    Moreover, administration of low-dose melanotan-2, an α-MSH receptor (MC4R) agonist, decreased food intake per body weight in Caps2-KO mice; no such effect was observed in the wildtype mice.
  2. 02AnimalAnimal study (in vivo)Efficacy outcome

    In wild-type mice, low-dose melanotan-2 did not decrease food intake per body weight.

    In plain wordsIn normal mice, a low dose of melanotan-2 did not reduce food intake per body weight.

    Peptide
    Melanotan II
    Outcome
    No significant changeFood intake per body weight after melanotan-2
    Study

    mousen: not reported in source

    Wild-type mice
    Outcome group
    Appetite and food intake · Metabolic and weight
    Studied dose
    low-doseAs given in this study (mouse).

    Source sentences

    Summary
    Moreover, administration of low-dose melanotan-2, an α-MSH receptor (MC4R) agonist, decreased food intake per body weight in Caps2-KO mice; no such effect was observed in the wildtype mice.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    10 Oct 2026, 09:43 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 03:04 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

PepBank is a research reference. Talk to a doctor before you use any peptide.