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Study · Randomized controlled trial · n = 60 · 2020

3 results

Effect of oxytocin infusion on reducing blood loss during abdominal myomectomy: A randomized controlled trial.

Ahmed M, Baqai S, Khushdil A, Ahmed F

JPMA. The Journal of the Pakistan Medical Association1 Jun 2020Cited by 2 (Europe PMC)

PMID32810088 (opens in a new tab)DOI10.5455/jpma.14026 (opens in a new tab)PepBankPUB-32810088
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study3

3 results from studies that gave the peptide. 3 results from people.

  1. 01HumanRandomized controlled trialEfficacy outcome

    In women undergoing abdominal myomectomy, oxytocin infusion gave significantly lower mean intra-operative blood loss than saline.

    In plain wordsIn women having fibroid surgery, an oxytocin drip led to less blood loss than a saline drip.

    Peptide
    Oxytocin
    Outcome
    DecreaseIntra-operative blood loss
    Study

    n = 60

    Comparator
    Normal saline infusion
    Analysis
    Primary
    Outcome group
    Bleeding and clotting · Reproductive and sexual health
    Studied dose
    30 units in 1000 ml normal saline at 15 units/hour · infusion · during surgeryAs given in this study (human).

    Measurements

    Mean blood loss
    409.67 ml
    oxytocin group
    Mean blood loss
    875.33 ml
    control group

    Source sentences

    Summary
    Mean intra-operative blood loss in the study group was 409.67±181.29ml which was significantly lower than the control group 875.33±284.71 (p<0.05).
    3 context sentences
    Summary · context
    The main outcome measure was intra-operative blood loss.
    Summary · context
    The single-blind randomised control trial was conducted at the Obstetrics and Gynaecology Department of Military Hospital, Rawalpindi, Pakistan, July 15, 2017, to January 15, 2018, and comprised women with intramural fibroids of American Society of Anaesthesia class I and II who were candidates for…
    Summary · context
    In the study group, an infusion of 30 units of oxytocin in 1000ml normal saline was given at the rate of 15 units/hour during surgery.
  2. 02HumanRandomized controlled trialEfficacy outcome

    In women undergoing abdominal myomectomy, mean surgery time differed significantly between the oxytocin and saline groups; the direction is not stated.

    In plain wordsIn women having fibroid surgery, the length of surgery differed between the oxytocin and saline groups; the abstract does not say which was longer.

    Peptide
    Oxytocin
    Outcome
    Direction not reportedSurgery time
    Study

    n = 60

    Comparator
    Normal saline infusion
    Outcome group
    Uterine fibroid outcomes · Reproductive and sexual health
    Studied dose
    30 units in 1000 ml normal saline at 15 units/hour · infusion · during surgeryAs given in this study (human).

    Source sentences

    Summary
    The mean surgery time also showed statistically significant difference between the two groups (p<0.05).
    2 context sentences
    Summary · context
    The single-blind randomised control trial was conducted at the Obstetrics and Gynaecology Department of Military Hospital, Rawalpindi, Pakistan, July 15, 2017, to January 15, 2018, and comprised women with intramural fibroids of American Society of Anaesthesia class I and II who were candidates for…
    Summary · context
    In the study group, an infusion of 30 units of oxytocin in 1000ml normal saline was given at the rate of 15 units/hour during surgery.
  3. 03HumanRandomized controlled trialEfficacy outcome

    In women undergoing abdominal myomectomy, fewer patients needed blood transfusion with oxytocin infusion than with saline.

    In plain wordsIn women having fibroid surgery, fewer needed a blood transfusion with an oxytocin drip than with a saline drip.

    Peptide
    Oxytocin
    Outcome
    DecreaseBlood transfusion requirement
    Study

    n = 60

    Comparator
    Normal saline infusion
    Outcome group
    Bleeding and clotting · Reproductive and sexual health
    Studied dose
    30 units in 1000 ml normal saline at 15 units/hour · infusion · during surgeryAs given in this study (human).

    Measurements

    Transfusion
    10%
    oxytocin group
    Transfusion
    36.6%
    control group

    Source sentences

    Summary
    In the study group, 3(10%) patients required blood transfusion, while blood was transfused to 11(36.6%) patients in the control group (p=0.046).
    2 context sentences
    Summary · context
    The single-blind randomised control trial was conducted at the Obstetrics and Gynaecology Department of Military Hospital, Rawalpindi, Pakistan, July 15, 2017, to January 15, 2018, and comprised women with intramural fibroids of American Society of Anaesthesia class I and II who were candidates for…
    Summary · context
    In the study group, an infusion of 30 units of oxytocin in 1000ml normal saline was given at the rate of 15 units/hour during surgery.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    11 Oct 2026, 01:30 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 02:48 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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