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Study · Systematic review · 2020

4 results

Potential shortcomings in current studies on the effect of intranasal oxytocin in Anorexia Nervosa and healthy controls - A systematic review and meta-analysis.

Hasselbalch KC, Lanng KR, Birkeland M, Sjögren M

Psychopharmacology18 Aug 2020Cited by 11 (Europe PMC)

PMID32809046 (opens in a new tab)DOI10.1007/s00213-020-05626-5 (opens in a new tab)PepBankPUB-32809046
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study4

4 results from studies that gave the peptide. 4 results from people.

  1. 01HumanSystematic reviewEfficacy outcome

    In a meta-analysis of trials in anorexia nervosa and healthy controls, intranasal oxytocin did not change attentional bias towards food images.

    In plain wordsIn pooled trials in people with anorexia nervosa and healthy people, nasal oxytocin did not change attention towards food images.

    Peptide
    Oxytocin
    Outcome
    No significant changeAttentional bias towards food images
    Study

    n: not reported in source

    Outcome group
    Cognition and memory · Mental health and mood
    Studied dose
    Dose not stated · intranasalAs given in this study (human).

    Measurements

    Effect size
    0.2
    Attentional bias towards food images

    Source sentences

    Summary
    Overall, IN-OT did not influence AB towards food images (effect size = 0.20 [- 0.16, 0.57], p = 0.28)
    1 context sentence
    Summary · context
    Six publications, reporting from 4 unique clinical trials, were included in this review.
  2. 02HumanSystematic reviewEfficacy outcome

    In a meta-analysis of trials in anorexia nervosa and healthy controls, intranasal oxytocin had no effect on emotion recognition.

    In plain wordsIn pooled trials in people with anorexia nervosa and healthy people, nasal oxytocin did not change emotion recognition.

    Peptide
    Oxytocin
    Outcome
    No significant changeEmotion recognition
    Study

    n: not reported in source

    Outcome group
    Cognition and memory · Mental health and mood
    Studied dose
    Dose not stated · intranasalAs given in this study (human).

    Source sentences

    Summary
    and had no effect on ER (effect size = - 0.01 [- 0.27, 0.26], p = 0.97)
    1 context sentence
    Summary · context
    Six publications, reporting from 4 unique clinical trials, were included in this review.
  3. 03HumanSystematic reviewEfficacy outcome

    In subgroup analyses of healthy controls and of patients with anorexia nervosa, intranasal oxytocin showed no significant effect on attentional bias.

    In plain wordsWhen healthy people and people with anorexia nervosa were looked at separately, nasal oxytocin did not change attention towards food images.

    Peptide
    Oxytocin
    Outcome
    No significant changeAttentional bias, subgroups of healthy controls and patients with anorexia nervosa
    Study

    n: not reported in source

    Outcome group
    Cognition and memory · Mental health and mood
    Studied dose
    Dose not stated · intranasalAs given in this study (human).

    Source sentences

    Summary
    Assessing HC and AN separately in subgroup analyses did not show any significant effect on AB and ER in neither of the subgroups.
    1 context sentence
    Summary · context
    Six publications, reporting from 4 unique clinical trials, were included in this review.
  4. 04HumanSystematic reviewEfficacy outcome

    In subgroup analyses of healthy controls and of patients with anorexia nervosa, intranasal oxytocin showed no significant effect on emotion recognition.

    In plain wordsWhen healthy people and people with anorexia nervosa were looked at separately, nasal oxytocin did not change emotion recognition.

    Peptide
    Oxytocin
    Outcome
    No significant changeEmotion recognition, subgroups of healthy controls and patients with anorexia nervosa
    Study

    n: not reported in source

    Outcome group
    Cognition and memory · Mental health and mood
    Studied dose
    Dose not stated · intranasalAs given in this study (human).

    Source sentences

    Summary
    Assessing HC and AN separately in subgroup analyses did not show any significant effect on AB and ER in neither of the subgroups.
    1 context sentence
    Summary · context
    Six publications, reporting from 4 unique clinical trials, were included in this review.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    11 Oct 2026, 01:30 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 02:48 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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