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Study · Randomized controlled trial · n = 94 · 2020

1 result

The effect of oxytocin on pupil response to naturalistic dynamic facial expressions.

Burley DT, Daughters K

Hormones and behavior6 Aug 2020Cited by 10 (Europe PMC)

Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study1

1 result from studies that gave the peptide. 1 result from people.

  1. 01HumanRandomized controlled trialEfficacy outcome

    In men, oxytocin nasal spray had no effect on pupil diameter in response to dynamic facial expressions versus placebo.

    In plain wordsIn men, oxytocin nasal spray did not change pupil size when viewing facial expressions compared with placebo.

    Peptide
    Oxytocin
    Outcome
    No significant changePupil diameter in response to dynamic facial expressions
    Study

    n = 94

    Comparator
    Placebo
    Outcome group
    Cognition and memory · Nervous system and cognition
    Studied dose
    Dose not stated · nasal sprayAs given in this study (human).

    Source sentences

    Summary
    Contrary to prediction, there was no effect of OT administration on pupil diameter.
    1 context sentence
    Summary · context
    Ninety-four male participants took part in the double-blind, placebo controlled, mixed-design study, in which they self-administered either an OT or PL nasal spray before viewing naturalistic dynamic facial expressions of emotion (happy, sad, fear and anger).

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    11 Oct 2026, 01:30 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 02:49 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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