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Study · Systematic review · 2020

2 results

Exogenous effects of oxytocin in five psychiatric disorders: a systematic review, meta-analyses and a personalized approach through the lens of the social salience hypothesis.

Peled-Avron L, Abu-Akel A, Shamay-Tsoory S

Neuroscience and biobehavioral reviews26 Apr 2020Cited by 55 (Europe PMC)

Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

2 results from studies that gave the peptide. 2 results from people.

  1. 01HumanSystematic reviewEfficacy outcome

    In people with schizophrenia, a meta-analysis found a small effect size for oxytocin efficacy.

    In plain wordsIn people with schizophrenia, a meta-analysis found only a small effect of oxytocin treatment.

    Peptide
    Oxytocin
    Outcome
    Direction not reportedOxytocin efficacy in schizophrenia
    Study

    n: not reported in source

    Outcome group
    Psychiatric symptoms · Mental health and mood
    Studied dose
    Dose not stated

    Source sentences

    Summary
    The meta-analyses revealed a small effect size of OT efficacy in schizophrenia
    1 context sentence
    Summary · context
    This systematic review and meta-analysis examines available evidence for the therapeutic role of OT in five psychiatric disorders characterized with difficulties in social abilities: autism spectrum disorder, schizophrenia, post-traumatic stress disorder, mood disorders and borderline personality disorder.
  2. 02HumanSystematic reviewEfficacy outcome

    In people with autism spectrum disorder, a meta-analysis found a small effect size for oxytocin on repetitive behaviors.

    In plain wordsIn people with autism spectrum disorder, a meta-analysis found only a small effect of oxytocin on repetitive behaviors.

    Peptide
    Oxytocin
    Outcome
    Direction not reportedOxytocin efficacy on repetitive behaviors in autism spectrum disorder
    Study

    n: not reported in source

    Outcome group
    Psychiatric symptoms · Mental health and mood
    Studied dose
    Dose not stated

    Source sentences

    Summary
    The meta-analyses revealed a small effect size of OT efficacy in schizophrenia and repetitive behaviors in ASD.
    1 context sentence
    Summary · context
    This systematic review and meta-analysis examines available evidence for the therapeutic role of OT in five psychiatric disorders characterized with difficulties in social abilities: autism spectrum disorder, schizophrenia, post-traumatic stress disorder, mood disorders and borderline personality disorder.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    9 Oct 2026, 18:17 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 02:49 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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