In healthy participants, Selank and Semax had general and specific effects on functional connectivity between the right amygdala and the right temporal cortex; the abstract gives no direction for Selank.
In plain wordsIn healthy adults, Selank changed how the right amygdala communicates with the right temporal cortex, as seen on brain scans.
- Peptide
- Selank
- Outcome
- Direction not reportedResting-state functional connectivity of the right amygdala with the right temporal cortex
- Study
n = 52
- Comparator
- Placebo
- Outcome group
- Brain and neuronal activity · Nervous system and cognition
- Studied dose
- Dose not stated · injectionAs given in this study (human).
Source sentences
Between-group alongwith between-condition differences were revealed in FC between the right amygdala and a region in fusiform, inferior and middle temporal as well as parahippocampal gyri in the right hemisphere.
3 context sentences(design, population, supporting numbers)
Post hoc analysis allowed us to define both general and specific effects of Selank and Semax on FC between the right amygdala and the right temporal cortex for the first time.
The present study was aimed at the assessment of effects of anxiolytic Selank and nootropic Semax on the whole-brain resting-state functional connectivity (FC) of each of the predefined regions of interest (ROIs) in 52 healthy participants.
Resting-state fMRI was carried out three times, namely before, after 5 and 20 min of the injection of either Semax, or Selank, or placebo.