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Study · Measured the body's own peptide · 2020

2 results

Relationship between rosacea and sleep.

Wang Z, Xie H, Gong Y, Ouyang Y, Deng F, Tang Y, Li J

The Journal of dermatology14 Apr 2020Cited by 28 (Europe PMC)

PMID32291809 (opens in a new tab)DOI10.1111/1346-8138.15339 (opens in a new tab)PepBankPUB-32291809
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

No result from this study comes from a test of the peptide.

Natural levels measured1

These results measure the body's own peptide. Nobody was given the peptide. They are not evidence about taking it. They are left out of key results, evidence counts and charts.

  1. 01AnimalEndogenous levelAnimal study (in vivo)Mechanism

    In mice with an LL‑37-induced rosacea-like phenotype, sleep deprivation increased expression of the body's own cathelicidin antimicrobial peptide.

    In plain wordsIn mice with rosacea-like skin, sleep deprivation raised the mice's own cathelicidin levels.

    Peptide
    LL-37
    Outcome
    IncreaseCathelicidin antimicrobial peptide expression with sleep deprivation
    Study

    mousen: not reported in source

    LL-37-induced rosacea-like phenotype with sleep deprivation
    Outcome group
    Inflammation markers · Skin and wound

    Source sentences

    Summary
    Furthermore, the LL-37-induced rosacea-like phenotype and sleep-deprivation mice models were applied, revealing that sleep deprivation aggravated the rosacea-like phenotype in mice, with higher expression of matrix metallopeptidase 9, Toll-like receptor 2, cathelicidin antimicrobial peptide and vasc…

    This result measures the body's own LL-37. Nobody was given the peptide. It is not evidence about taking it.

Studies that did not test the peptide alone1

In this study, LL-37 was a lab tool or a carrier, part of a mix, or the subject of a lab method. These results are not evidence about taking LL-37.

  1. 02AnimalNot a test of LL-37 aloneAnimal study (in vivo)Efficacy outcome

    In mice challenged with LL‑37 to induce a rosacea-like phenotype, sleep deprivation aggravated the phenotype; LL‑37 was the challenge, not the treatment.

    In plain wordsIn mice with LL‑37-induced rosacea-like skin, sleep deprivation made the skin condition worse.

    Peptide
    LL-37
    Outcome
    IncreaseRosacea-like phenotype with sleep deprivation
    Study

    mousen: not reported in source

    LL-37-induced rosacea-like phenotype with sleep deprivation
    Outcome group
    Skin and hair · Skin and wound

    Source sentences

    Summary
    Furthermore, the LL-37-induced rosacea-like phenotype and sleep-deprivation mice models were applied, revealing that sleep deprivation aggravated the rosacea-like phenotype in mice, with higher expression of matrix metallopeptidase 9, Toll-like receptor 2, cathelicidin antimicrobial peptide and vasc…

    In this study, LL-37 was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking LL-37.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 3Current

    11 Oct 2026, 00:50 UTC

    Study results updated

  2. Version 2

    9 Oct 2026, 03:03 UTC

    Study data updated · source update from Europe PMC

  3. Version 1

    9 Oct 2026, 02:57 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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