In T2D patients with binge eating disorder, dulaglutide reduced binge eating behaviour more than gliclazide.
In plain wordsIn patients with diabetes and binge eating disorder, dulaglutide reduced binge eating more than gliclazide.
- Peptide
- Dulaglutide (Trulicity)
- Outcome
- DecreaseBinge eating behaviour
- Study
n: not reported in source
- Comparator
- Gliclazide
- Outcome group
- Appetite and food intake · Metabolic and weight
- Studied dose
- 1.5 mg weekly · 12 weeksAs given in this study (human).
Source sentences
After 12 weeks patients treated with dulaglutide had grater reduction of binge eating behaviour (p < 0.0001), body weight (p < 0,0001), BMI (p < 0.0001), percentage fat mass (p < 0.0001) and HbA1c (p = 0.009) than patients treated with gliclazide.
1 context sentence(design, population, supporting numbers)
This was a pilot open label, prospective controlled study. Inclusion criteria were: Age ≤65, HbA1c between 7.5 and 9% on metformin therapy alone, normal renal function and diagnosis of BED. Patients were randomly assigned to receive either Dulaglutide 1,5 mg/sett or Gliclazide 60 mg for 12 weeks.