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Study · In vitro (cells) · 2020

2 results

Enhanced biological properties of collagen/chitosan-coated poly(ε-caprolactone) scaffold by surface modification with GHK-Cu peptide and 58S bioglass.

Molavi AM, Sadeghi-Avalshahr A, Nokhasteh S, Naderi-Meshkin H

Progress in biomaterials4 Apr 2020Cited by 10 (Europe PMC)

PMID32248401 (opens in a new tab)PMCIDPMC7289912 (opens in a new tab)DOI10.1007/s40204-020-00129-0 (opens in a new tab)PepBankPUB-32248401
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

2 results from studies that gave the peptide. No result from this study comes from people.

  1. 01LabIn vitro (cells)Efficacy outcome

    In vitro, cell proliferation on GHK‑Cu-coated scaffolds increased significantly at day 3 compared with uncoated poly(ε-caprolactone)/collagen/chitosan scaffolds (day 7 for bioactive glass-coated scaffolds).

    In plain wordsIn lab tests, cells grew more on scaffolds coated with GHK‑Cu than on uncoated scaffolds.

    Peptide
    GHK-Cu
    Outcome
    IncreaseCell proliferation at day 3
    Study

    n: not reported in source

    Collagen/chitosan-coated electrospun polycaprolactone scaffold, in vitro
    Comparator
    Poly(ε-caprolactone)/collagen/chitosan scaffold
    Outcome group
    Wound healing · Skin and wound
    Studied dose
    1-mM solutionAs given in this study.

    Source sentences

    Summary
    Compared to poly(ε-caprolactone)/collagen/chitosan, the cell proliferation of GHK-Cu and bioactive glass-coated (concentrations of 0.01 and 0.1) scaffolds increased significantly at days 3 and 7, respectively.
    1 context sentence
    Summary · context
    Similarly, GHK-Cu-coated scaffolds were prepared by pipetting adequate amount of 1-mM solution of peptide (in milli-Q) on the surface of scaffolds.
  2. 02LabIn vitro (cells)Efficacy outcome

    In vitro, the antibacterial activity of the GHK‑Cu-coated scaffold was superior to the uncoated scaffold and the bioactive glass-coated scaffolds.

    In plain wordsIn lab tests, the scaffold coated with GHK‑Cu blocked bacteria better than the uncoated scaffold and the glass-coated scaffolds.

    Peptide
    GHK-Cu
    Outcome
    IncreaseAntibacterial activity
    Study

    n: not reported in source

    Collagen/chitosan-coated electrospun polycaprolactone scaffold, in vitro
    Comparator
    Uncoated scaffold and bioactive glass-coated scaffolds
    Outcome group
    Infection and antimicrobial activity · Infection
    Studied dose
    1-mM solutionAs given in this study.

    Source sentences

    Summary
    the antibacterial activity of GHK-Cu-coated sample turned out to be superior.
    1 context sentence
    Summary · context
    Similarly, GHK-Cu-coated scaffolds were prepared by pipetting adequate amount of 1-mM solution of peptide (in milli-Q) on the surface of scaffolds.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 3Current

    9 Oct 2026, 18:17 UTC

    Study results updated

  2. Version 2

    9 Oct 2026, 03:03 UTC

    Study data updated · source update from Europe PMC

  3. Version 1

    9 Oct 2026, 02:56 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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