In adults with mild to moderate depression, vitamin D supplementation did not significantly change serum oxytocin versus placebo; the between-group difference was insignificant.
In plain wordsIn adults with depression, vitamin D did not clearly change the body's own oxytocin levels compared with placebo.
- Peptide
- Oxytocin
- Outcome
- No significant changeSerum oxytocin concentration change
- Study
n = 56
- Comparator
- Placebo
- Outcome group
- Endogenous peptide levels · Mental health and mood
Source sentences
Oxytocin concentrations were significantly reduced in controls (-6.49±13.69 ng/mL, P = 0.01), but between -group differences were insignificant.
1 context sentence(design, population, supporting numbers)
An 8-week double-blind randomized clinical trial was conducted on 56 subjects with mild to moderate depression, aged 43.0 ± 1.15yrs. The patients were randomly allocated into two groups: intervention (50,000 IU cholecalciferol/2wks) and control (placebo).
This result measures the body's own Oxytocin. Nobody was given the peptide. It is not evidence about taking it.