In rats with traumatic brain injury, the glyproline peptide MGHPPGP (Semax sequence) corrected the activity indicators of the nuclear organizer regions in tongue epitheliocytes.
In plain wordsIn rats with brain injury, the peptide corrected nuclear activity markers in tongue lining cells.
- Peptide
- Semax
- Outcome
- Direction not reportedNuclear organizer region activity in tongue epitheliocytes (AgNOR)
- Study
ratn: not reported in source
Wistar male rats, traumatic brain injury (weight drop)- Outcome group
- Cell proliferation and differentiation · Gastrointestinal
- Studied dose
- 1 mg/kg · intraperitoneal · 3 h and days 2, 3, 4, 5 after injuryAs given in this study (rat).
Source sentences
MGHPPGP peptide corrected the activity indicators of the nuclear organizer regions in epitheliocytes of the tongue.
2 context sentences(design, population, supporting numbers)
The effect of glyproline-containing peptide MGHPPGP (Met-Glu-His-Phe-Pro-Gly-Pro) was studied in experiments on male Wistar rats with modeled traumatic brain injury.
The peptide was administered intraperitoneally in a dose of 1 mg/kg in 3 h and on days 2, 3, 4, 5 after injury.