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Study · Animal study (in vivo) · 2020

7 results

miR-709 inhibits GHRP6 induced GH synthesis by targeting PRKCA in pituitary.

Cheng Y, Chen T, Song J, Qi Q, Wang C, Xi Q, Liu S, Hao L, Zhang Y

Molecular and cellular endocrinology19 Feb 2020Cited by 15 (Europe PMC)

PMID32084499 (opens in a new tab)DOI10.1016/j.mce.2020.110763 (opens in a new tab)PepBankPUB-32084499
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study7

7 results from studies that gave the peptide. No result from this study comes from people.

  1. 01AnimalAnimal study (in vivo)Mechanism

    In vivo assays, GHRP6 increased PKCα expression.

    In plain wordsIn animals of an unspecified species, GHRP6 increased PKCα expression.

    Peptide
    GHRP-6
    Outcome
    IncreasePKCα expression in vivo
    Study

    n: not reported in source

    In vivo assays, species not stated
    Outcome group
    Growth hormone and IGF-1 · Endocrine and hormones
    Studied dose
    Dose not stated

    Source sentences

    Summary
    At last, GHRP6 increased PKCα and GH expression but reduced miR-709 expression in vitro and vivo assays
    1 context sentence
    Summary · context
    At last, GHRP6 increased PKCα and GH expression but reduced miR-709 expression in vitro and vivo assays, and this conclusion was further confirmed by the result of GHRP6 attenuated the inhibition of miR-709 on GH expression.
  2. 02AnimalAnimal study (in vivo)Mechanism

    In vivo assays, GHRP6 increased GH expression.

    In plain wordsIn animals of an unspecified species, GHRP6 increased growth hormone expression.

    Peptide
    GHRP-6
    Outcome
    IncreaseGH expression in vivo
    Study

    n: not reported in source

    In vivo assays, species not stated
    Outcome group
    Growth hormone and IGF-1 · Endocrine and hormones
    Studied dose
    Dose not stated

    Source sentences

    Summary
    At last, GHRP6 increased PKCα and GH expression but reduced miR-709 expression in vitro and vivo assays
    1 context sentence
    Summary · context
    At last, GHRP6 increased PKCα and GH expression but reduced miR-709 expression in vitro and vivo assays, and this conclusion was further confirmed by the result of GHRP6 attenuated the inhibition of miR-709 on GH expression.
  3. 03AnimalAnimal study (in vivo)Mechanism

    In vivo assays, GHRP6 reduced miR-709 expression.

    In plain wordsIn animals of an unspecified species, GHRP6 reduced miR-709 expression.

    Peptide
    GHRP-6
    Outcome
    DecreasemiR-709 expression in vivo
    Study

    n: not reported in source

    In vivo assays, species not stated
    Outcome group
    Growth hormone and IGF-1 · Endocrine and hormones
    Studied dose
    Dose not stated

    Source sentences

    Summary
    At last, GHRP6 increased PKCα and GH expression but reduced miR-709 expression in vitro and vivo assays
    1 context sentence
    Summary · context
    At last, GHRP6 increased PKCα and GH expression but reduced miR-709 expression in vitro and vivo assays, and this conclusion was further confirmed by the result of GHRP6 attenuated the inhibition of miR-709 on GH expression.
  4. 04LabIn vitro (cells)Mechanism

    In vitro, GHRP6 increased PKCα expression.

    In plain wordsIn lab tests, GHRP6 increased PKCα expression.

    Peptide
    GHRP-6
    Outcome
    IncreasePKCα expression in vitro
    Study

    n: not reported in source

    In vitro assays
    Outcome group
    Growth hormone and IGF-1 · Endocrine and hormones
    Studied dose
    Dose not stated

    Source sentences

    Summary
    At last, GHRP6 increased PKCα and GH expression but reduced miR-709 expression in vitro and vivo assays
    1 context sentence
    Summary · context
    At last, GHRP6 increased PKCα and GH expression but reduced miR-709 expression in vitro and vivo assays, and this conclusion was further confirmed by the result of GHRP6 attenuated the inhibition of miR-709 on GH expression.
  5. 05LabIn vitro (cells)Mechanism

    In vitro, GHRP6 increased GH expression.

    In plain wordsIn lab tests, GHRP6 increased growth hormone expression.

    Peptide
    GHRP-6
    Outcome
    IncreaseGH expression in vitro
    Study

    n: not reported in source

    In vitro assays
    Outcome group
    Growth hormone and IGF-1 · Endocrine and hormones
    Studied dose
    Dose not stated

    Source sentences

    Summary
    At last, GHRP6 increased PKCα and GH expression but reduced miR-709 expression in vitro and vivo assays
    1 context sentence
    Summary · context
    At last, GHRP6 increased PKCα and GH expression but reduced miR-709 expression in vitro and vivo assays, and this conclusion was further confirmed by the result of GHRP6 attenuated the inhibition of miR-709 on GH expression.
  6. 06LabIn vitro (cells)Mechanism

    In vitro, GHRP6 reduced miR-709 expression.

    In plain wordsIn lab tests, GHRP6 reduced miR-709 expression.

    Peptide
    GHRP-6
    Outcome
    DecreasemiR-709 expression in vitro
    Study

    n: not reported in source

    In vitro assays
    Outcome group
    Growth hormone and IGF-1 · Endocrine and hormones
    Studied dose
    Dose not stated

    Source sentences

    Summary
    At last, GHRP6 increased PKCα and GH expression but reduced miR-709 expression in vitro and vivo assays
    1 context sentence
    Summary · context
    At last, GHRP6 increased PKCα and GH expression but reduced miR-709 expression in vitro and vivo assays, and this conclusion was further confirmed by the result of GHRP6 attenuated the inhibition of miR-709 on GH expression.
  7. 07LabIn vitro (cells)Mechanism

    In experimental assays, GHRP6 attenuated miR-709-mediated inhibition of GH expression.

    In plain wordsIn lab tests, GHRP6 reduced the inhibition of growth hormone expression by miR-709.

    Peptide
    GHRP-6
    Outcome
    IncreasemiR-709-mediated GH suppression
    Study

    n: not reported in source

    Outcome group
    Growth hormone and IGF-1 · Endocrine and hormones
    Studied dose
    Dose not stated

    Source sentences

    Summary
    and this conclusion was further confirmed by the result of GHRP6 attenuated the inhibition of miR-709 on GH expression.
    1 context sentence
    Summary · context
    At last, GHRP6 increased PKCα and GH expression but reduced miR-709 expression in vitro and vivo assays, and this conclusion was further confirmed by the result of GHRP6 attenuated the inhibition of miR-709 on GH expression.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    21 Oct 2026, 15:58 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 03:13 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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