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Study · Randomized controlled trial · 2020

3 results

Oxytocin alters the effect of payoff but not base rate in emotion perception.

Wu Q, Mao J, Li J

Psychoneuroendocrinology8 Feb 2020Cited by 2 (Europe PMC)

PMID32070797 (opens in a new tab)DOI10.1016/j.psyneuen.2020.104608 (opens in a new tab)PepBankPUB-32070797
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study3

3 results from studies that gave the peptide. 3 results from people.

  1. 01HumanRandomized controlled trialEfficacy outcome

    In healthy men, intranasal oxytocin induced a categorization bias in emotion perception under payoff manipulation compared with placebo.

    In plain wordsIn healthy men, oxytocin shifted how faces were judged when the cost of mistakes changed, compared with placebo.

    Peptide
    Oxytocin
    Outcome
    Direction not reportedEmotion categorization bias under payoff manipulation
    Study

    n: not reported in source

    Comparator
    Placebo
    Outcome group
    Cognition and memory · Nervous system and cognition
    Studied dose
    24 IU · intranasalAs given in this study (human).

    Source sentences

    Summary
    Compared to the placebo group, oxytocin specifically induced a categorization bias under the payoff, but not base rate manipulation.
    1 context sentence
    Summary · context
    One hundred and twenty-two healthy male adults (sixty-two in Experiment 1 and sixty in Experiment 2, respectively) received 24 international units (IU) of intranasal oxytocin or placebo (between-subjects) in a randomized and double-blind study.
  2. 02HumanRandomized controlled trialEfficacy outcome

    In healthy men, intranasal oxytocin did not induce a categorization bias under base rate manipulation compared with placebo.

    In plain wordsIn healthy men, oxytocin did not shift face judgments when the likelihood of emotions changed, compared with placebo.

    Peptide
    Oxytocin
    Outcome
    No significant changeEmotion categorization bias under base rate manipulation
    Study

    n: not reported in source

    Comparator
    Placebo
    Outcome group
    Cognition and memory · Nervous system and cognition
    Studied dose
    24 IU · intranasalAs given in this study (human).

    Source sentences

    Summary
    Compared to the placebo group, oxytocin specifically induced a categorization bias under the payoff, but not base rate manipulation.
    1 context sentence
    Summary · context
    One hundred and twenty-two healthy male adults (sixty-two in Experiment 1 and sixty in Experiment 2, respectively) received 24 international units (IU) of intranasal oxytocin or placebo (between-subjects) in a randomized and double-blind study.
  3. 03HumanRandomized controlled trialEfficacy outcome

    In healthy men, intranasal oxytocin had no effect on confidence ratings in emotion perception.

    In plain wordsIn healthy men, oxytocin did not change how confident people were in their face judgments.

    Peptide
    Oxytocin
    Outcome
    No significant changeConfidence rating (metacognitive sensitivity)
    Study

    n: not reported in source

    Comparator
    Placebo
    Outcome group
    Cognition and memory · Nervous system and cognition
    Studied dose
    24 IU · intranasalAs given in this study (human).

    Source sentences

    Summary
    In contrast, oxytocin had no effect on subjects' confidence rating, indicating that the metacognitive sensitivity can be dissociated from emotion perception.
    1 context sentence
    Summary · context
    One hundred and twenty-two healthy male adults (sixty-two in Experiment 1 and sixty in Experiment 2, respectively) received 24 international units (IU) of intranasal oxytocin or placebo (between-subjects) in a randomized and double-blind study.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    11 Oct 2026, 00:50 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 02:48 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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