In women with borderline personality disorder and healthy controls, oxytocin had no significant effect on heartbeat-evoked potential amplitude compared with placebo.
In plain wordsIn women with borderline personality disorder and healthy women, oxytocin did not change the brain's response to the heartbeat, compared with placebo.
- Peptide
- Oxytocin
- Outcome
- No significant changeHeartbeat-evoked potential amplitude
- Study
n = 113
- Comparator
- Placebo
- Outcome group
- Heart function · Nervous system and cognition
- Studied dose
- 24 IUAs given in this study (human).
Source sentences
However, oxytocin had no significant effect on HEP amplitude.
2 context sentences(design, population, supporting numbers)
Fifty-three medication-free women with a DSM-IV diagnosis of BPD and sixty healthy female controls (HCs) participated in the study.
In a randomized, double-blind placebo-controlled trial, participants self-administered either 24 I.U. of oxytocin or placebo and took part in a 5-minute resting-state electrocardiogram (ECG) with parallel electroencephalogram (EEG) measurement.