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Study · Not a test of the peptide alone · 2020

3 results

Preoperative growth hormone (GH) peak values during a GH releasing peptide-2 test reflect the severity of hypopituitarism and the postoperative recovery of GH secretion in patients with non-functioning pituitary adenomas.

Soga A, Fukuda I, Kobayashi S, Tahara S, Morita A, Sugihara H

Endocrine journal26 Nov 2019Cited by 4 (Europe PMC)

PMID31776295 (opens in a new tab)DOI10.1507/endocrj.ej19-0288 (opens in a new tab)PepBankPUB-31776295
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study3

No result from this study comes from a test of the peptide.

Studies that did not test the peptide alone3

In this study, GHRP-2 was a lab tool or a carrier, part of a mix, or the subject of a lab method. These results are not evidence about taking GHRP-2.

  1. 01HumanNot a test of GHRP-2 aloneObservational studyOther

    In 76 patients with non-functioning pituitary adenoma, a lower peak GH release during a GHRP‑2 test was associated with more anterior pituitary hormone deficiencies.

    In plain wordsIn 76 patients with pituitary tumours, a lower peak growth hormone on a GHRP‑2 test went with more missing pituitary hormones.

    Peptide
    GHRP-2
    Outcome
    Not applicablePeak GH during GHRP-2 test and number of pituitary hormone deficiencies
    Study

    n = 76

    Outcome group
    Growth hormone and IGF-1 · Endocrine and hormones

    Source sentences

    Summary
    A lower peak GH release during a GHRP-2 test was associated with a higher number of anterior pituitary hormone deficiencies across all 76 patients.
    1 context sentence
    Summary · context
    Among the 76 patients with NFPA who were admitted to our institution, 36 patients (mean age, 61 years; male/female, n = 23/n = 13) were diagnosed with severe AGHD based on a preoperative GHRP-2 test.

    In this study, GHRP-2 was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking GHRP-2.

  2. 02HumanNot a test of GHRP-2 aloneObservational studyOther

    After surgery, seven patients in the moderate peak GH group (M) and none in the low group (L) no longer had severe adult GH deficiency.

    In plain wordsAfter surgery, seven patients with a higher GHRP‑2 test peak, and none with a lower peak, no longer had severe growth hormone deficiency.

    Peptide
    GHRP-2
    Outcome
    Not applicablePostoperative recovery from severe AGHD by preoperative peak GH group
    Study

    n = 36

    Comparator
    Group L (peak GH below median) versus group M
    Outcome group
    Growth hormone and IGF-1 · Endocrine and hormones

    Source sentences

    Summary
    Postoperatively, seven in group M and no patient in group L were assessed as having no longer severe AGHD, respectively.
    1 context sentence
    Summary · context
    Among the 76 patients with NFPA who were admitted to our institution, 36 patients (mean age, 61 years; male/female, n = 23/n = 13) were diagnosed with severe AGHD based on a preoperative GHRP-2 test.

    In this study, GHRP-2 was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking GHRP-2.

  3. 03HumanNot a test of GHRP-2 aloneObservational studyOther

    Patients with low peak GH on the GHRP‑2 test were significantly older and more gonadotropin and ACTH deficient than those with moderate peak GH.

    In plain wordsPatients with a lower peak growth hormone on a GHRP‑2 test were older and had more missing pituitary hormones than those with a higher peak.

    Peptide
    GHRP-2
    Outcome
    Not applicableGroup L versus group M clinical characteristics by peak GH on GHRP-2 test
    Study

    n = 36

    Comparator
    Group M
    Outcome group
    Growth hormone and IGF-1 · Endocrine and hormones

    Source sentences

    Summary
    Compared with group M, group L patients were significantly older and more gonadotropin and ACTH deficient.
    1 context sentence
    Summary · context
    Among the 76 patients with NFPA who were admitted to our institution, 36 patients (mean age, 61 years; male/female, n = 23/n = 13) were diagnosed with severe AGHD based on a preoperative GHRP-2 test.

    In this study, GHRP-2 was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking GHRP-2.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    13 Oct 2026, 21:44 UTC

    Study results updated

  2. Version 1

    13 Oct 2026, 16:31 UTC

    First added · source update from Europe PMC

Subjects

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