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Study · Not a test of the peptide alone · 2020

1 result

Hypothalamic C2-domain protein involved in MC4R trafficking and control of energy balance.

Gavini CK, Cook TM, Rademacher DJ, Mansuy-Aubert V

Metabolism: clinical and experimental27 Oct 2019Cited by 23 (Europe PMC)

PMID31666192 (opens in a new tab)DOI10.1016/j.metabol.2019.153990 (opens in a new tab)PepBankPUB-31666192
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: CC BY-NC-ND. Results still quote short attributed sentences.

Results from this study1

No result from this study comes from a test of the peptide.

Studies that did not test the peptide alone1

In this study, Melanotan II was a lab tool or a carrier, part of a mix, or the subject of a lab method. These results are not evidence about taking Melanotan II.

  1. 01AnimalNot a test of Melanotan II aloneAnimal study (in vivo)Mechanism

    In mice lacking C2CD5, the acute response to melanotan II injected into the paraventricular hypothalamus was smaller than in wild-type mice.

    In plain wordsIn mice without C2CD5, the short-term response to melanotan II injected into the brain was smaller than in normal mice.

    Peptide
    Melanotan II
    Outcome
    DecreaseAcute response to melanotan II injection into the paraventricular hypothalamus in C2CD5 knockout mice
    Study

    mousen: not reported in source

    C2CD5 whole-body knockout mice
    Comparator
    Wild-type mice
    Outcome group
    Appetite and food intake · Metabolic and weight

    Source sentences

    Summary
    5) C2CD5KO mice exhibit decreased acute responses to MTII injection into the PVH.

    In this study, Melanotan II was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Melanotan II.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 3Current

    27 Oct 2026, 16:36 UTC

    Study data updated · source update from Europe PMC

  2. Version 2

    10 Oct 2026, 09:43 UTC

    Study results updated

  3. Version 1

    9 Oct 2026, 03:04 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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