A novel semen supplement (SuinFort) improves sow fertility after artificial insemination.

Ngula J, Manjarín R, Martínez-Pastor F, Alegre B, Tejedor I, Brown T, Piñán J, Kirkwood RN, Domínguez JC

Animal reproduction science13 Sept 2019Cited by 3 (Europe PMC)

PMID31635779DOI10.1016/j.anireprosci.2019.106193PepBankPUB-31635779

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Summary

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Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study3

No result from this study comes from a test of the peptide.

Studies that did not test the peptide alone3

In this study, Oxytocin was a lab tool or a carrier, part of a mix, or the subject of a lab method. These results are not evidence about taking Oxytocin.

01HumanNot a test of Oxytocin aloneRandomized controlled trialEfficacy outcome
In multiparous sows, semen supplemented with SuinFort (oxytocin, lecirelin and caffeine) raised farrowing rate versus unsupplemented semen.
In plain wordsIn sows, a semen additive with oxytocin, lecirelin and caffeine raised farrowing rate compared with no additive.
Peptide
Oxytocin
Outcome
IncreaseFarrowing rate
Study
pign: not reported in source
Comparator
No supplementation
Outcome group
Sex hormones and fertility · Reproductive and sexual health
Measurements
Farrowing rate
90.7%
SuinFort
Farrowing rate
87.2%
control
Source sentences
Summary
Supplementation with SuinFort resulted in greater fertility both by increasing farrowing rate 87.2% ± 0.7 to 90.7% ± 1.0 (P < 0.001)
1 context sentence(design, population, supporting numbers)
Summary · context
For 2 years, a total of 1159 sows were assigned to be artificial inseminated (AI) either with semen supplemented with the additive (2 IU oxytocin, 5 μg lecirelin, 2 mM caffeine, n = 830 AI) or with no supplementation (Control, n = 2422 AI).
In this study, Oxytocin was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Oxytocin.
Report a problemFND-3163577901
02HumanNot a test of Oxytocin aloneRandomized controlled trialEfficacy outcome
In multiparous sows, semen supplemented with SuinFort (oxytocin, lecirelin and caffeine) increased litter size versus unsupplemented semen.
In plain wordsIn sows, a semen additive with oxytocin, lecirelin and caffeine gave larger litters than no additive.
Peptide
Oxytocin
Outcome
IncreaseLitter size
Study
pign: not reported in source
Comparator
No supplementation
Outcome group
Sex hormones and fertility · Reproductive and sexual health
Measurements
Litter size
14.4 piglets
SuinFort
Litter size
13.8 piglets
control
Source sentences
Summary
Supplementation with SuinFort resulted in greater fertility both by increasing farrowing rate 87.2% ± 0.7 to 90.7% ± 1.0 (P < 0.001) and litter size from 13.8 ± 0.1 to 14.4 ± 0.1 (P < 0.001).
1 context sentence(design, population, supporting numbers)
Summary · context
For 2 years, a total of 1159 sows were assigned to be artificial inseminated (AI) either with semen supplemented with the additive (2 IU oxytocin, 5 μg lecirelin, 2 mM caffeine, n = 830 AI) or with no supplementation (Control, n = 2422 AI).
In this study, Oxytocin was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Oxytocin.
Report a problemFND-3163577902
03LabNot a test of Oxytocin aloneEx vivo tissueEfficacy outcome
In boar semen in vitro, aliquots with SuinFort (oxytocin, lecirelin and caffeine) showed a small decrease in semen quality versus control aliquots.
In plain wordsIn lab tests on boar semen, the additive with oxytocin, lecirelin and caffeine slightly lowered sperm quality compared with control semen.
Peptide
Oxytocin
Outcome
DecreaseIn vitro sperm quality
Study
pign: not reported in source
Boar semen doses
Comparator
No supplementation
Outcome group
Sex hormones and fertility · Reproductive and sexual health
Source sentences
Summary
For aliquots with SuinFort, there was a small decrease in semen quality.
1 context sentence(design, population, supporting numbers)
Summary · context
To test if there was a direct effect of SuinFort on spermatozoa, an in vitro experiment was conducted using semen doses from 10 boars.
In this study, Oxytocin was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Oxytocin.
Report a problemFND-3163577903

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Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

Version 2Current
11 Oct 2026, 01:30 UTC
Study results updated
Version 1
9 Oct 2026, 02:49 UTC
First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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