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Study · Randomized controlled trial · n = 38 · 2019

3 results

Oxytocin reduces post-stress sweet snack intake in women without attenuating salivary cortisol.

Burmester V, Gibson EL, Butler G, Bailey A, Terry P

Physiology & behavior16 Oct 2019Cited by 24 (Europe PMC)

PMID31628930 (opens in a new tab)DOI10.1016/j.physbeh.2019.112704 (opens in a new tab)PepBankPUB-31628930
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study3

3 results from studies that gave the peptide. 3 results from people.

  1. 01HumanRandomized controlled trialEfficacy outcome

    In women, 24 IU intranasal oxytocin reduced sweet fatty snack intake after stress versus placebo.

    In plain wordsIn women, oxytocin reduced sweet fatty snack eating after stress, compared with placebo.

    Peptide
    Oxytocin
    Outcome
    DecreaseSweet fatty snack intake after stress
    Study

    n = 38

    Comparator
    Placebo
    Outcome group
    Appetite and food intake · Metabolic and weight
    Studied dose
    24 IU · intranasal · single dose per sessionAs given in this study (human).

    Source sentences

    Summary
    Oxytocin significantly reduced sweet fatty snack intake independently of any effect on salivary cortisol
    1 context sentence
    Summary · context
    The present study adopted a double-blind, repeated measures and fully concealed crossover protocol in which 38 women self-administered 24 IU of oxytocin or placebo intranasally, ate lunch, and underwent two consecutive stress tests.
  2. 02HumanRandomized controlled trialEfficacy outcome

    In women, salivary cortisol declined over time at a similar rate after oxytocin or placebo.

    In plain wordsIn women, cortisol fell at a similar rate after oxytocin and after placebo.

    Peptide
    Oxytocin
    Outcome
    No significant changeSalivary cortisol over time
    Study

    n = 38

    Comparator
    Placebo
    Outcome group
    Stress hormones · Endocrine and hormones
    Studied dose
    24 IU · intranasal · single dose per sessionAs given in this study (human).

    Source sentences

    Summary
    which declined over time at a similar rate after either drug or placebo.
    1 context sentence
    Summary · context
    The present study adopted a double-blind, repeated measures and fully concealed crossover protocol in which 38 women self-administered 24 IU of oxytocin or placebo intranasally, ate lunch, and underwent two consecutive stress tests.
  3. 03HumanRandomized controlled trialEfficacy outcome

    In women, oxytocin slightly reduced ratings of sweet taste versus placebo, but only in self-reported stress eaters.

    In plain wordsOxytocin slightly lowered sweet taste ratings, but only in women who said they eat when stressed, compared with placebo.

    Peptide
    Oxytocin
    Outcome
    DecreaseRatings of sweet taste in self-reported stress eaters
    Study

    n: not reported in source

    Comparator
    Placebo
    Outcome group
    Appetite and food intake · Metabolic and weight
    Studied dose
    24 IU · intranasal · single dose per sessionAs given in this study (human).

    Source sentences

    Summary
    Ratings of sweet taste were slightly reduced by oxytocin, but only in self-reported stress eaters.
    2 context sentences
    Summary · context
    Salivary cortisol was measured throughout the test period every 15 min.
    Summary · context
    The present study adopted a double-blind, repeated measures and fully concealed crossover protocol in which 38 women self-administered 24 IU of oxytocin or placebo intranasally, ate lunch, and underwent two consecutive stress tests.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    11 Oct 2026, 01:30 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 02:48 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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