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Study · Not a test of the peptide alone · 2019

5 results

[An analysis of the peptide composition of a 'light' peptide fraction of cerebrolysin].

Gromova OA, Torshin IY, Zgoda VG, Tikhonova OV

Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova1 Jan 2019Cited by 3 (Europe PMC)

PMID31626174 (opens in a new tab)DOI10.17116/jnevro201911908175 (opens in a new tab)PepBankPUB-31626174
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study5

No result from this study comes from a test of the peptide.

Studies that did not test the peptide alone5

In this study, Cerebrolysin was a lab tool or a carrier, part of a mix, or the subject of a lab method. These results are not evidence about taking Cerebrolysin.

  1. 01LabNot a test of Cerebrolysin aloneIn vitro (cell-free)Other

    In lab tests of the light Cerebrolysin fraction, researchers identified 14 635 peptide sequences corresponding to 1643 porcine neuronal proteins.

    In plain wordsIn lab tests, the light Cerebrolysin fraction contained 14 635 identified peptide sequences.

    Peptide
    Cerebrolysin
    Outcome
    Not applicablePeptide sequences identified
    Study

    n: not reported in source

    Outcome group
    Product quality and purity · Pharmacology

    Source sentences

    Summary
    The amino acid sequences of 14 635 peptides corresponding to the 1643 porcine proteome neuronal proteins are identified.
    1 context sentence
    Summary · context
    Mass spectrometry (MS) with orbital ion traps and modern de novo MS-sequencing algorithms was performed.

    In this study, Cerebrolysin was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Cerebrolysin.

  2. 02LabNot a test of Cerebrolysin aloneIn vitro (cell-free)Other

    In lab tests, Cerebrolysin contained Leu- and Met-enkephalins and fragments of orexin, neuropeptide VF, galanin and nerve growth factor.

    In plain wordsIn lab tests, Cerebrolysin contained enkephalins and fragments of several neuropeptides and nerve growth factor.

    Peptide
    Cerebrolysin
    Outcome
    Not applicableNeurotrophic peptide composition
    Study

    n: not reported in source

    Outcome group
    Product quality and purity · Pharmacology

    Source sentences

    Summary
    The results confirm the presence of Leu- and Met-enkephalins, fragments of neuropeptide orexin, neuropeptide VF, galanin and nerve growth factor that have a neurotrophic effect.
    1 context sentence
    Summary · context
    Mass spectrometry (MS) with orbital ion traps and modern de novo MS-sequencing algorithms was performed.

    In this study, Cerebrolysin was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Cerebrolysin.

  3. 03Computer modelNot a test of Cerebrolysin aloneIn silicoMechanism

    In human proteome annotation analysis, peptides from the light Cerebrolysin fraction could mimic corresponding human peptides.

    In plain wordsComputer analysis suggested that peptides from the light Cerebrolysin fraction could mimic human peptides.

    Peptide
    Cerebrolysin
    Outcome
    Not applicableHuman peptide mimicry
    Study

    n: not reported in source

    Outcome group
    Receptor activity and mechanism · Pharmacology

    Source sentences

    Summary
    An analysis of the human proteome annotation shows that these peptides can mimic the corresponding human peptides.
    1 context sentence
    Summary · context
    Mass spectrometry (MS) with orbital ion traps and modern de novo MS-sequencing algorithms was performed.

    In this study, Cerebrolysin was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Cerebrolysin.

  4. 04Computer modelNot a test of Cerebrolysin aloneIn silicoOther

    In proteome analysis of the light Cerebrolysin fraction, 405 fragments corresponded to 300 known biologically active peptides.

    In plain wordsComputer analysis linked 405 Cerebrolysin peptide fragments to 300 known biologically active peptides.

    Peptide
    Cerebrolysin
    Outcome
    Not applicableBiologically active peptide correspondence
    Study

    n: not reported in source

    Outcome group
    Product quality and purity · Pharmacology

    Source sentences

    Summary
    In particular, 405 peptide fragments correspond to 300 known biologically active peptides, including fragments of antibacterial peptides (defensins, histatins), immunomodulatory (granulin, manserin) and vasoactive (endothelin, VIP) peptides.
    1 context sentence
    Summary · context
    Mass spectrometry (MS) with orbital ion traps and modern de novo MS-sequencing algorithms was performed.

    In this study, Cerebrolysin was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Cerebrolysin.

  5. 05Computer modelNot a test of Cerebrolysin aloneIn silicoMechanism

    In proteome analysis, 8953 of 14 635 Cerebrolysin peptides could modulate 275 human signaling proteins.

    In plain wordsComputer analysis suggested that 8953 Cerebrolysin peptides could modulate 275 human signaling proteins.

    Peptide
    Cerebrolysin
    Outcome
    Not applicableSignaling protein modulation prediction
    Study

    n: not reported in source

    Outcome group
    Receptor activity and mechanism · Pharmacology

    Source sentences

    Summary
    At the same time, 8953 of 14 635 peptides can modulate the activity of 275 human signaling proteins, including kinases CDK1, CDK2, TGFBR2, GSK3, MTOR, pro-apoptotic caspases CASP1, CASP3 and CASP6 etc.
    1 context sentence
    Summary · context
    Mass spectrometry (MS) with orbital ion traps and modern de novo MS-sequencing algorithms was performed.

    In this study, Cerebrolysin was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Cerebrolysin.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    14 Oct 2026, 05:02 UTC

    Study results updated

  2. Version 1

    14 Oct 2026, 01:46 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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