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Study · Not a test of the peptide alone · 2019

3 results

Electrophoretic deposition of GHK-Cu loaded MSN-chitosan coatings with pH-responsive release of copper and its bioactivity.

Ning C, Jiajia J, Meng L, Hongfei Q, Xianglong W, Tingli L

Materials science & engineering. C, Materials for biological applications5 Jul 2019Cited by 15 (Europe PMC)

PMID31500015 (opens in a new tab)DOI10.1016/j.msec.2019.109746 (opens in a new tab)PepBankPUB-31500015
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study3

No result from this study comes from a test of the peptide.

Studies that did not test the peptide alone3

In this study, GHK-Cu was a lab tool or a carrier, part of a mix, or the subject of a lab method. These results are not evidence about taking GHK-Cu.

  1. 01LabNot a test of GHK-Cu aloneIn vitro (cells)Activity measurement

    Through controlled release of copper ions, the GHK‑Cu loaded coating inhibited adhesion of bacteria.

    In plain wordsIn lab tests, the GHK‑Cu loaded coating reduced bacteria sticking to its surface.

    Peptide
    GHK-Cu
    Outcome
    DecreaseBacterial adhesion on coating
    Study

    n: not reported in source

    Outcome group
    Infection and antimicrobial activity · Infection

    Source sentences

    Summary
    Through the controllable release of Cu2+, the coating achieved not only inhibited adhesion of bacteria
    1 context sentence
    Summary · context
    In this study, we prepared mesoporous silica nanoparticles (MSN) and MSN-COOH with uniform sphere size (~100 nm) and developed multifunctional chitosan coatings loaded with MSN@GHK-Cu (glycyl-L-histidyl-l-lysine-Cu2+) as a suitable strategy by electrophoretic deposition (EPD).

    In this study, GHK-Cu was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking GHK-Cu.

  2. 02LabNot a test of GHK-Cu aloneIn vitro (cells)Safety outcome

    The GHK‑Cu loaded coating had good cytocompatibility.

    In plain wordsIn lab tests, cells tolerated the GHK‑Cu loaded coating well.

    Peptide
    GHK-Cu
    Outcome
    Not applicableCytocompatibility of coating
    Study

    n: not reported in source

    Outcome group
    Adverse events · Musculoskeletal

    Source sentences

    Summary
    but also had good cytocompatibility
    1 context sentence
    Summary · context
    In this study, we prepared mesoporous silica nanoparticles (MSN) and MSN-COOH with uniform sphere size (~100 nm) and developed multifunctional chitosan coatings loaded with MSN@GHK-Cu (glycyl-L-histidyl-l-lysine-Cu2+) as a suitable strategy by electrophoretic deposition (EPD).

    In this study, GHK-Cu was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking GHK-Cu.

  3. 03LabNot a test of GHK-Cu aloneIn vitro (cell-free)Other

    Release of copper ions from the GHK‑Cu loaded coating on the titanium surface depended on the pH value.

    In plain wordsIn lab tests, how much copper the GHK‑Cu coating released depended on pH.

    Peptide
    GHK-Cu
    Outcome
    Not applicablepH-dependent copper ion release from coating
    Study

    n: not reported in source

    Outcome group
    Pharmacokinetics · Pharmacology

    Source sentences

    Summary
    The functional activity of Cu2+ releasing from the surface was dependent on the pH value of the titanium surface.
    1 context sentence
    Summary · context
    In this study, we prepared mesoporous silica nanoparticles (MSN) and MSN-COOH with uniform sphere size (~100 nm) and developed multifunctional chitosan coatings loaded with MSN@GHK-Cu (glycyl-L-histidyl-l-lysine-Cu2+) as a suitable strategy by electrophoretic deposition (EPD).

    In this study, GHK-Cu was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking GHK-Cu.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 3Current

    9 Oct 2026, 18:17 UTC

    Study results updated

  2. Version 2

    9 Oct 2026, 03:03 UTC

    Study data updated · source update from Europe PMC

  3. Version 1

    9 Oct 2026, 02:56 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

Publication types

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