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Study · Randomized controlled trial · n = 170 · 2020

3 results

Oxytocin modulation of self-referential processing is partly replicable and sensitive to oxytocin receptor genotype.

Zhao W, Luo R, Sindermann C, Li J, Wei Z, Zhang Y, Liu C, Le J, Quintana DS, Montag C, Becker B, Kendrick KM

Progress in neuro-psychopharmacology & biological psychiatry12 Aug 2019Cited by 13 (Europe PMC)

PMID31415827 (opens in a new tab)DOI10.1016/j.pnpbp.2019.109734 (opens in a new tab)PepBankPUB-31415827
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study3

3 results from studies that gave the peptide. 3 results from people.

  1. 01HumanRandomized controlled trialEfficacy outcome

    In 170 men, intranasal oxytocin reduced decision time in self-other trait judgment in the whole sample.

    In plain wordsIn men, oxytocin shortened decision time when judging traits of self and others.

    Peptide
    Oxytocin
    Outcome
    DecreaseDecision time in self-other trait judgment, whole sample
    Study

    n = 170

    Outcome group
    Social behavior and cognition · Nervous system and cognition
    Studied dose
    24 IU · intranasalAs given in this study (human).

    Source sentences

    Summary
    We confirmed that in the whole sample oxytocin influenced self-other distinction in terms of reduced decision time.
    1 context sentence
    Summary · context
    intranasal oxytocin (24 IU) reduces the self-referential bias in a large sample of n = 170 male subjects
  2. 02HumanRandomized controlled trialEfficacy outcome

    Oxytocin reduced decision time only in carriers of the oxytocin receptor rs53576 G allele.

    In plain wordsOxytocin shortened decision time only in men who carried one specific oxytocin receptor gene variant.

    Peptide
    Oxytocin
    Outcome
    DecreaseDecision time in rs53576 G carriers
    Study

    n: not reported in source

    Outcome group
    Social behavior and cognition · Nervous system and cognition
    Studied dose
    24 IU · intranasalAs given in this study (human).

    Source sentences

    Summary
    However, oxytocin only influenced decision time in rs53576 G carriers
  3. 03HumanRandomized controlled trialEfficacy outcome

    Oxytocin effects on subsequent memory performance were found only in rs2268498 TT homozygotes; the direction was not stated.

    In plain wordsOxytocin effects on later memory showed up only in men with one specific oxytocin receptor gene variant.

    Peptide
    Oxytocin
    Outcome
    Direction not reportedSubsequent memory performance in rs2268498 TT homozygotes
    Study

    n: not reported in source

    Outcome group
    Social behavior and cognition · Nervous system and cognition
    Studied dose
    24 IU · intranasalAs given in this study (human).

    Source sentences

    Summary
    whereas effects on subsequent memory performance were only found in rs2268498 TT homozygotes.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    11 Oct 2026, 00:50 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 02:48 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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