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Study · Measured the body's own peptide · 2019

2 results

Trauma exposure, posttraumatic stress disorder and oxytocin: A meta-analytic investigation of endogenous concentrations and receptor genotype.

Engel S, Klusmann H, Laufer S, Pfeifer AC, Ditzen B, van Zuiden M, Knaevelsrud C, Schumacher S

Neuroscience and biobehavioral reviews11 Aug 2019Cited by 19 (Europe PMC)

PMID31412270 (opens in a new tab)DOI10.1016/j.neubiorev.2019.08.003 (opens in a new tab)PepBankPUB-31412270
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

No result from this study comes from a test of the peptide.

Natural levels measured2

These results measure the body's own peptide. Nobody was given the peptide. They are not evidence about taking it. They are left out of key results, evidence counts and charts.

  1. 01HumanEndogenous levelSystematic reviewOther

    In a meta-analysis, the body's own oxytocin concentrations did not differ between people with PTSD and healthy individuals.

    In plain wordsA pooled analysis found the body's own oxytocin levels were not different in people with PTSD and healthy people.

    Peptide
    Oxytocin
    Outcome
    No significant changeEndogenous oxytocin concentration in PTSD versus healthy individuals
    Study

    n: not reported in source

    Comparator
    Healthy individuals
    Outcome group
    Anxiety and mood · Mental health and mood

    Source sentences

    Summary
    Endogenous oxytocin concentrations did not differ between PTSD patients and healthy individuals.
    1 context sentence
    Summary · context
    We meta-analytically compared oxytocin parameters between traumatized and non-traumatized individuals (k = 17) and individuals with and without PTSD (k = 8), and correlated oxytocin with trauma exposure (k = 16) and PTSD symptoms (k = 8).

    This result measures the body's own Oxytocin. Nobody was given the peptide. It is not evidence about taking it.

  2. 02HumanEndogenous levelSystematic reviewOther

    In a meta-analysis, the remaining effects on the body's own oxytocin (trauma comparisons and correlations with trauma exposure and PTSD symptoms) were heterogeneous.

    In plain wordsA pooled analysis found mixed, inconsistent results for the body's own oxytocin levels in relation to trauma and PTSD symptoms.

    Peptide
    Oxytocin
    Outcome
    MixedEndogenous oxytocin in traumatized versus non-traumatized people and its correlation with trauma exposure and PTSD symptoms
    Study

    n: not reported in source

    Outcome group
    Anxiety and mood · Mental health and mood

    Source sentences

    Summary
    The remaining effects on endogenous oxytocin were heterogeneous.
    1 context sentence
    Summary · context
    We meta-analytically compared oxytocin parameters between traumatized and non-traumatized individuals (k = 17) and individuals with and without PTSD (k = 8), and correlated oxytocin with trauma exposure (k = 16) and PTSD symptoms (k = 8).

    This result measures the body's own Oxytocin. Nobody was given the peptide. It is not evidence about taking it.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    11 Oct 2026, 01:30 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 02:48 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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