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Study · Animal study (in vivo) · rat · 2019

3 results

An integrated approach to study the molecular aspects of regulatory peptides biological mechanism.

Vyunova TV, Andreeva LA, Shevchenko KV, Myasoedov NF

Journal of labelled compounds & radiopharmaceuticals1 Aug 2019Cited by 6 (Europe PMC)

PMID31325343 (opens in a new tab)DOI10.1002/jlcr.3785 (opens in a new tab)PepBankPUB-31325343
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study3

3 results from studies that gave the peptide. No result from this study comes from people.

  1. 01AnimalAnimal study (in vivo)Mechanism

    In rat neuronal plasma membranes after complex stress, Semax modulated [3H]acetylcholine specific binding to some of its receptors in a dose-dependent manner.

    In plain wordsIn rats after stress, Semax changed acetylcholine binding to some receptors, depending on dose.

    Peptide
    Semax
    Outcome
    Direction not reported[3H]Ach specific binding to receptors
    Study

    ratn: not reported in source

    rat model of stress-induced memory and behavior impairment, neuronal plasma membranes
    Outcome group
    Receptor activity and mechanism · Nervous system and cognition
    Studied dose
    Dose not stated

    Source sentences

    Summary
    We showed the ability of Semax to modulate in a dose-dependent manner [3 H]Ach and [3 H]GABA specific binding to some of its corresponding receptors
    1 context sentence
    Summary · context
    In this issue we used heptapeptide Semax as a model regulatory peptide, [3 H]Ach and [3 H]GABA as an effector molecules, and the rat model of stress-induced memory and behavior impairment as a morbid state.
  2. 02AnimalAnimal study (in vivo)Mechanism

    In rat neuronal plasma membranes after complex stress, Semax modulated [3H]GABA specific binding to some of its receptors in a dose-dependent manner.

    In plain wordsIn rats after stress, Semax changed GABA binding to some receptors, depending on dose.

    Peptide
    Semax
    Outcome
    Direction not reported[3H]GABA specific binding to receptors
    Study

    ratn: not reported in source

    rat model of stress-induced memory and behavior impairment, neuronal plasma membranes
    Outcome group
    Receptor activity and mechanism · Nervous system and cognition
    Studied dose
    Dose not stated

    Source sentences

    Summary
    We showed the ability of Semax to modulate in a dose-dependent manner [3 H]Ach and [3 H]GABA specific binding to some of its corresponding receptors
    1 context sentence
    Summary · context
    In this issue we used heptapeptide Semax as a model regulatory peptide, [3 H]Ach and [3 H]GABA as an effector molecules, and the rat model of stress-induced memory and behavior impairment as a morbid state.
  3. 03AnimalAnimal study (in vivo)Mechanism

    In rat neuronal plasma membranes after complex stress, Semax affected the number of [3H]GABA specific binding sites.

    In plain wordsIn rats after stress, Semax changed the number of GABA binding sites on nerve cell membranes.

    Peptide
    Semax
    Outcome
    Direction not reportedNumber of [3H]GABA specific binding sites
    Study

    ratn: not reported in source

    rat model of stress-induced memory and behavior impairment, neuronal plasma membranes
    Outcome group
    Receptor activity and mechanism · Nervous system and cognition
    Studied dose
    Dose not stated

    Source sentences

    Summary
    as well as to affect the number of [3 H]GABA specific binding places on rat neurons plasmatic membranes after complex stress exposure
    1 context sentence
    Summary · context
    In this issue we used heptapeptide Semax as a model regulatory peptide, [3 H]Ach and [3 H]GABA as an effector molecules, and the rat model of stress-induced memory and behavior impairment as a morbid state.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    9 Oct 2026, 19:08 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 03:04 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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