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Study · Animal study (in vivo) · rat · 2019

9 results

Effect of cerebrolysin on bladder function after spinal cord injury in female Wistar rats.

Abolhasanpour N, Eidi A, Hajebrahimi S, Reyhani-Rad S, Hashim H

International journal of urology : official journal of the Japanese Urological Association17 Jul 2019Cited by 8 (Europe PMC)

PMID31317583 (opens in a new tab)DOI10.1111/iju.14059 (opens in a new tab)PepBankPUB-31317583
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study9

9 results from studies that gave the peptide. No result from this study comes from people.

  1. 01AnimalAnimal study (in vivo)Efficacy outcome

    In female rats with spinal cord injury, cerebrolysin at 1 mL/kg for 1 week slightly improved urodynamic parameters.

    In plain wordsIn female rats with spinal cord injury, cerebrolysin slightly improved bladder measurements.

    Peptide
    Cerebrolysin
    Outcome
    Direction not reportedUrodynamic parameters
    Study

    ratn: not reported in source

    Complete spinal cord transection in female Wistar rats
    Outcome group
    Urinary continence and bladder function · Kidney and urinary
    Studied dose
    1 mL/kg · intraperitoneal · 1 weekAs given in this study (rat).

    Source sentences

    Summary
    Cerebrolysin injection in a dose of 1 mL/kg for 1 week showed a slight improvement in urodynamic parameters.
    1 context sentence
    Summary · context
    After induction of complete transection at T9-T10 spinal vertebrae
  2. 02AnimalAnimal study (in vivo)Efficacy outcome

    In female rats with spinal cord injury, cerebrolysin at 2.5 mL/kg for 1 week increased bladder contractions.

    In plain wordsIn female rats with spinal cord injury, cerebrolysin increased bladder contractions.

    Peptide
    Cerebrolysin
    Outcome
    IncreaseBladder contractions
    Study

    ratn: not reported in source

    Complete spinal cord transection in female Wistar rats
    Outcome group
    Urinary continence and bladder function · Kidney and urinary
    Studied dose
    2.5 mL/kg · intraperitoneal · 1 weekAs given in this study (rat).

    Source sentences

    Summary
    However, infusion of 2.5 and 5 mL/kg cerebrolysin for 1 week caused an elevation in contractions and a decrease in compliance.
    1 context sentence
    Summary · context
    After induction of complete transection at T9-T10 spinal vertebrae
  3. 03AnimalAnimal study (in vivo)Efficacy outcome

    In female rats with spinal cord injury, cerebrolysin at 5 mL/kg for 1 week increased bladder contractions.

    In plain wordsIn female rats with spinal cord injury, cerebrolysin increased bladder contractions.

    Peptide
    Cerebrolysin
    Outcome
    IncreaseBladder contractions
    Study

    ratn: not reported in source

    Complete spinal cord transection in female Wistar rats
    Outcome group
    Urinary continence and bladder function · Kidney and urinary
    Studied dose
    5 mL/kg · intraperitoneal · 1 weekAs given in this study (rat).

    Source sentences

    Summary
    However, infusion of 2.5 and 5 mL/kg cerebrolysin for 1 week caused an elevation in contractions and a decrease in compliance.
    1 context sentence
    Summary · context
    After induction of complete transection at T9-T10 spinal vertebrae
  4. 04AnimalAnimal study (in vivo)Efficacy outcome

    In female rats with spinal cord injury, cerebrolysin at 2.5 mL/kg for 1 week decreased bladder compliance.

    In plain wordsIn female rats with spinal cord injury, cerebrolysin reduced bladder compliance.

    Peptide
    Cerebrolysin
    Outcome
    DecreaseBladder compliance
    Study

    ratn: not reported in source

    Complete spinal cord transection in female Wistar rats
    Outcome group
    Urinary continence and bladder function · Kidney and urinary
    Studied dose
    2.5 mL/kg · intraperitoneal · 1 weekAs given in this study (rat).

    Source sentences

    Summary
    However, infusion of 2.5 and 5 mL/kg cerebrolysin for 1 week caused an elevation in contractions and a decrease in compliance.
    1 context sentence
    Summary · context
    After induction of complete transection at T9-T10 spinal vertebrae
  5. 05AnimalAnimal study (in vivo)Efficacy outcome

    In female rats with spinal cord injury, cerebrolysin at 5 mL/kg for 1 week decreased bladder compliance.

    In plain wordsIn female rats with spinal cord injury, cerebrolysin reduced bladder compliance.

    Peptide
    Cerebrolysin
    Outcome
    DecreaseBladder compliance
    Study

    ratn: not reported in source

    Complete spinal cord transection in female Wistar rats
    Outcome group
    Urinary continence and bladder function · Kidney and urinary
    Studied dose
    5 mL/kg · intraperitoneal · 1 weekAs given in this study (rat).

    Source sentences

    Summary
    However, infusion of 2.5 and 5 mL/kg cerebrolysin for 1 week caused an elevation in contractions and a decrease in compliance.
    1 context sentence
    Summary · context
    After induction of complete transection at T9-T10 spinal vertebrae
  6. 06AnimalAnimal study (in vivo)Efficacy outcome

    In female rats with spinal cord injury, long-term cerebrolysin at 2.5 mL/kg improved compliance despite relative contractions.

    In plain wordsIn female rats with spinal cord injury, long-term cerebrolysin improved bladder compliance despite contractions.

    Peptide
    Cerebrolysin
    Outcome
    IncreaseLong-term bladder compliance
    Study

    ratn: not reported in source

    Complete spinal cord transection in female Wistar rats
    Outcome group
    Urinary continence and bladder function · Kidney and urinary
    Studied dose
    2.5 mL/kg · intraperitonealAs given in this study (rat).

    Source sentences

    Summary
    In long-term 2.5 mL/kg cerebrolysin injection, an improvement in compliance was observed, despite relative contractions.
    1 context sentence
    Summary · context
    After induction of complete transection at T9-T10 spinal vertebrae
  7. 07AnimalAnimal study (in vivo)Efficacy outcome

    In female rats with spinal cord injury, bladder pressure after 2.5 mL/kg cerebrolysin for 4 weeks resembled the control group.

    In plain wordsIn female rats with spinal cord injury, bladder pressure with cerebrolysin was similar to the control group.

    Peptide
    Cerebrolysin
    Outcome
    Direction not reportedBladder pressure pattern
    Study

    ratn: not reported in source

    Complete spinal cord transection in female Wistar rats
    Comparator
    Control group
    Outcome group
    Urinary continence and bladder function · Kidney and urinary
    Studied dose
    2.5 mL/kg · intraperitoneal · 4 weeksAs given in this study (rat).

    Source sentences

    Summary
    Furthermore, the bladder pressure pattern in the 2.5 mL/kg infused rats for 4 weeks was similar to the control group, but in the group receiving 5 mL/kg cerebrolysin for 4 weeks, reduced bladder contractions and function were observed.
    1 context sentence
    Summary · context
    After induction of complete transection at T9-T10 spinal vertebrae
  8. 08AnimalAnimal study (in vivo)Efficacy outcome

    In female rats with spinal cord injury, cerebrolysin at 5 mL/kg for 4 weeks reduced bladder contractions.

    In plain wordsIn female rats with spinal cord injury, cerebrolysin reduced bladder contractions.

    Peptide
    Cerebrolysin
    Outcome
    DecreaseBladder contractions
    Study

    ratn: not reported in source

    Complete spinal cord transection in female Wistar rats
    Outcome group
    Urinary continence and bladder function · Kidney and urinary
    Studied dose
    5 mL/kg · intraperitoneal · 4 weeksAs given in this study (rat).

    Source sentences

    Summary
    Furthermore, the bladder pressure pattern in the 2.5 mL/kg infused rats for 4 weeks was similar to the control group, but in the group receiving 5 mL/kg cerebrolysin for 4 weeks, reduced bladder contractions and function were observed.
    1 context sentence
    Summary · context
    After induction of complete transection at T9-T10 spinal vertebrae
  9. 09AnimalAnimal study (in vivo)Efficacy outcome

    In female rats with spinal cord injury, cerebrolysin at 5 mL/kg for 4 weeks reduced bladder function.

    In plain wordsIn female rats with spinal cord injury, cerebrolysin reduced bladder function.

    Peptide
    Cerebrolysin
    Outcome
    DecreaseBladder function
    Study

    ratn: not reported in source

    Complete spinal cord transection in female Wistar rats
    Outcome group
    Urinary continence and bladder function · Kidney and urinary
    Studied dose
    5 mL/kg · intraperitoneal · 4 weeksAs given in this study (rat).

    Source sentences

    Summary
    Furthermore, the bladder pressure pattern in the 2.5 mL/kg infused rats for 4 weeks was similar to the control group, but in the group receiving 5 mL/kg cerebrolysin for 4 weeks, reduced bladder contractions and function were observed.
    1 context sentence
    Summary · context
    After induction of complete transection at T9-T10 spinal vertebrae

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    14 Oct 2026, 05:02 UTC

    Study results updated

  2. Version 1

    14 Oct 2026, 01:46 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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