In patients with silicosis who got anti-infection treatment, adding thymalfasin significantly increased peripheral blood CD4+ cell numbers after one week compared with before treatment.
In plain wordsIn people with silicosis, thymalfasin added to standard anti-infection care raised blood CD4+ immune cell numbers after one week compared with before treatment.
- Peptide
- Thymosin alpha-1
- Outcome
- IncreasePeripheral blood CD4+ cell number after one week
- Study
n = 40
- Comparator
- Before treatment
- Outcome group
- Immune response · Immune and inflammation
- Studied dose
- Dose not stated · 1 weekAs given in this study (human).
Source sentences
(2) In the treatment group, the number of CD4+ cells in peripheral blood was significantly higher after one week of treatment, when compared to that before treatment, and the difference was statistically significant (P<0.05).
2 context sentences(design, population, supporting numbers)
A total of 80 silicosis patients were enrolled in the study, randomly divided into two groups: treatment group and control group (n=40, each group).
Patients in the treatment group additionally received thymalfasin.