In extramammary Paget's disease and squamous cell carcinoma, the percentage of cells producing the body's own LL37 was significantly higher in invasive than in non-invasive lesions.
In plain wordsIn skin cancers, invasive tumours had more cells making the body's own LL37 than non-invasive ones.
- Peptide
- LL-37
- Outcome
- IncreasePercentage of LL37-producing cells in invasive versus non-invasive EMPD and SCC
- Study
n: not reported in source
- Comparator
- Non-invasive EMPD and SCC
- Outcome group
- Cancer cell invasion and metastasis · Cancer
Source sentences
Immunohistochemical staining showed that the percentage of LL37-producing cells was significantly increased in invasive EMPD and SCC compared to that in non-invasive EMPD and SCC.
1 context sentence(design, population, supporting numbers)
In addition, to investigate the stromal factors that might affect ETC, immunohistochemical staining for LL37, periostin (POSTN), MMP12, and MMP28 was performed.
This result measures the body's own LL-37. Nobody was given the peptide. It is not evidence about taking it.